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10.1016/j.bja.2020.08.023

http://scihub22266oqcxt.onion/10.1016/j.bja.2020.08.023
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32988602!7455111!32988602
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suck abstract from ncbi


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pmid32988602      Br+J+Anaesth 2020 ; 125 (6): 872-879
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  • Safety and 30-day outcomes of tracheostomy for COVID-19: a prospective observational cohort study #MMPMID32988602
  • ä
  • Br J Anaesth 2020[Dec]; 125 (6): 872-879 PMID32988602show ga
  • BACKGROUND: The role of tracheostomy in coronavirus disease 2019 (COVID-19) is unclear, with several consensus guidelines advising against this practice. We developed both a dedicated airway team and coordinated education programme to facilitate ward management of tracheostomised COVID-19 patients. Here, we report outcomes in the first 100 COVID-19 patients who underwent tracheostomy at our institution. METHODS: This was a prospective observational cohort study of patients confirmed to have COVID-19 who required mechanical ventilation at Queen Elizabeth Hospital, Birmingham, UK. The primary outcome measure was 30-day survival, accounting for severe organ dysfunction (Acute Physiology and Chronic Health [APACHE]-II score>17). Secondary outcomes included duration of ventilation, ICU stay, and healthcare workers directly involved in tracheostomy care acquiring COVID-19. RESULTS: A total of 164 patients with COVID-19 were admitted to the ICU between March 9, 2020 and April 21, 2020. A total of 100 patients (mean [standard deviation] age: 55 [12] yr; 29% female) underwent tracheostomy; 64 (age: 57 [14] yr; 25% female) did not undergo tracheostomy. Despite similar APACHE-II scores, 30-day survival was higher in 85/100 (85%) patients after tracheostomy, compared with 27/64 (42%) non-tracheostomised patients relative risk: 3.9 (95% confidence intervals [CI]: 2.3-6.4); P<0.0001. In patients with APACHE-II scores >/=17, 68/100 (68%) tracheotomised patients survived, compared with 12/64 (19%) non-tracheotomised patients (P<0.001). Tracheostomy within 14 days of intubation was associated with shorter duration of ventilation (mean difference: 6.0 days [95% CI: 3.1-9.0]; P<0.0001) and ICU stay (mean difference: 6.7 days [95% CI: 3.7-9.6]; P<0.0001). No healthcare workers developed COVID-19. CONCLUSION: Independent of the severity of critical illness from COVID-19, 30-day survival was higher and ICU stay shorter in patients receiving tracheostomy. Early tracheostomy appears to be safe in COVID-19.
  • |APACHE[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |Cohort Studies[MESH]
  • |Coronavirus Infections/*therapy[MESH]
  • |Critical Care[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Length of Stay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Patient Care Team[MESH]
  • |Patient Safety[MESH]
  • |Patient Selection[MESH]
  • |Pneumonia, Viral/*therapy[MESH]
  • |Prospective Studies[MESH]
  • |Respiration, Artificial/methods[MESH]
  • |Survival Analysis[MESH]
  • |Tracheostomy/*adverse effects/*methods[MESH]
  • |Treatment Outcome[MESH]


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