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10.3390/ph13100268 http://scihub22266oqcxt.onion/10.3390/ph13100268 32987721!7598704!32987721     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmaceuticals+(Basel) 2020 ; 13 (10): ä Nephropedia Template TP {{tp|p=32987721|t=2020. Imaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI Contrast Agents |pdf=|usr=}}{{32987721}} gab.com Text Imaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI Contrast Agents JO: Pharmaceuticals (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32987721 #FOAvip Paramagnetic metal ion complexes, mostly based on gadolinium (Gd(3+)), have been used for over 30 years as magnetic resonance imaging (MRI) contrast agents. Gd(3+)-based contrast agents have a strong influence on T(1) relaxation times and are consequently the most commonly used agents in both the clinical and research environments. Zinc is an essential element involved with over 3000 different cellular proteins, and disturbances in tissue levels of zinc have been linked to a wide range of pathologies, including Alzheimer's disease, prostate cancer, and diabetes mellitus. MR contrast agents that respond to the presence of Zn(2+) in vivo offer the possibility of imaging changes in Zn(2+) levels in real-time with the superior spatial resolution offered by MRI. Such responsive agents, often referred to as smart agents, are typically composed of a paramagnetic metal ion with a ligand encapsulating it and one or more chelating units that selectively bind with the analyte of interest. Translation of these agents into clinical radiology is the next goal. In this review, we discuss Gd(3+)-based MR contrast agents that respond to a change in local Zn(2+) concentration. Twit Text FOAVip Imaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI Contrast Agents ????Pharmaceuticals (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=32987721 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32987721 #FOAvip English Wikipedia <ref>{{Cite pmid|32987721}}</ref> Imaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI Contrast Agents #MMPMID32987721 Khalighinejad P; Parrott D; Sherry AD Pharmaceuticals (Basel) 2020[Sep]; 13 (10): ä PMID32987721show ga Paramagnetic metal ion complexes, mostly based on gadolinium (Gd(3+)), have been used for over 30 years as magnetic resonance imaging (MRI) contrast agents. Gd(3+)-based contrast agents have a strong influence on T(1) relaxation times and are consequently the most commonly used agents in both the clinical and research environments. Zinc is an essential element involved with over 3000 different cellular proteins, and disturbances in tissue levels of zinc have been linked to a wide range of pathologies, including Alzheimer's disease, prostate cancer, and diabetes mellitus. MR contrast agents that respond to the presence of Zn(2+) in vivo offer the possibility of imaging changes in Zn(2+) levels in real-time with the superior spatial resolution offered by MRI. Such responsive agents, often referred to as smart agents, are typically composed of a paramagnetic metal ion with a ligand encapsulating it and one or more chelating units that selectively bind with the analyte of interest. Translation of these agents into clinical radiology is the next goal. In this review, we discuss Gd(3+)-based MR contrast agents that respond to a change in local Zn(2+) concentration. äImaging Tissue Physiology In Vivo by Use of Metal Ion-Responsive MRI C(epmc).pdf DeepDyve Pubget Overpricing