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suck abstract from ncbi


10.1016/j.cjco.2020.09.016

http://scihub22266oqcxt.onion/10.1016/j.cjco.2020.09.016
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32984798!7502228!32984798
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suck abstract from ncbi

pmid32984798      CJC+Open 2021 ; 3 (1): 91-100
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  • Impact of Right Ventricular Dysfunction on Mortality in Patients Hospitalized With COVID-19, According to Race #MMPMID32984798
  • Moody WE; Mahmoud-Elsayed HM; Senior J; Gul U; Khan-Kheil AM; Horne S; Banerjee A; Bradlow WM; Huggett R; Hothi SS; Shahid M; Steeds RP
  • CJC Open 2021[Jan]; 3 (1): 91-100 PMID32984798show ga
  • BACKGROUND: Epidemiologic studies suggest that Black, Asian, and minority ethnic (BAME) patients may be at risk of worse outcomes from coronavirus disease-2019 (COVID-19), but the pathophysiological drivers for this association are unknown. This study sought to investigate the relationship between findings on echocardiography, mortality, and race in COVID-19 pneumonia. METHODS: This was a multicentre, retrospective, observational study including 164 adults (aged 61 +/- 13 years; 78% male; 36% BAME) hospitalized with COVID-19 undergoing echocardiography between March 16 and May 9, 2020 at 3 days (interquartile range 2-5) from admission. The primary outcome was all-cause mortality. RESULTS: After a median follow-up of 31 days (interquartile range 14-42 days), 66 (40%) patients had died. The right ventricle was dilated in 62 (38%) patients, and 58 (35%) patients had right ventricular (RV) systolic dysfunction. Only 2 (1%) patients had left ventricular (LV) dilatation, and 133 (81%) had normal or hyperdynamic LV systolic function. Reduced tricuspid annulus planar systolic excursion was associated with elevated D-dimer (rho = -0.18, P = 0.025) and high-sensitivity cardiac Troponin (rho = -0.30, P < 0.0001). Reduced RV systolic function (hazard ratio 1.80; 95% confidence interval, 1.05-3.09; P = 0.032) was an independent predictor of all-cause mortality after adjustment for demographic and clinical risk factors. Comparing white and BAME individuals, there were no differences in echocardiography findings, biomarkers, or mortality. CONCLUSIONS: In patients hospitalized with COVID-19 pneumonia, reduced RV systolic function is prevalent and associated with all-cause mortality. There is, however, no racial variation in the early findings on echocardiography, biomarkers, or mortality.
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