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10.3389/fcell.2020.00856 http://scihub22266oqcxt.onion/10.3389/fcell.2020.00856 32984339!7479061!32984339     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32984339&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Front+Cell+Dev+Biol 2020 ; 8 (?): 856 Nephropedia Template TP {{tp|p=32984339|t=2020. Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction |pdf=|usr=}}{{32984339}} gab.com Text Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction JO: Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=32984339 #FOAvip The COVID-19 pandemic is a global health crisis that requires the application of interdisciplinary research to address numerous knowledge gaps including molecular strategies to prevent viral reproduction in affected individuals. In response to the Frontiers Research Topic, "Coronavirus disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management, and Public Health Response," this Hypothesis article proposes a novel therapeutic strategy to repurpose metabotropic glutamate 5 receptor (mGluR(5)) inhibitors to interfere with viral hijacking of the host protein synthesis machinery. We review pertinent background on SARS-CoV-2, fragile X syndrome (FXS) and metabotropic glutamate receptor 5 (mGluR(5)) and provide a mechanistic-based hypothesis and preliminary data to support testing mGluR(5) inhibitors in COVID-19 research. Twit Text FOAVip Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction ????Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=32984339 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32984339 #FOAvip English Wikipedia <ref>{{Cite pmid|32984339}}</ref> Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction #MMPMID32984339 Westmark CJ; Kiso M; Halfmann P; Westmark PR; Kawaoka Y Front Cell Dev Biol 2020[]; 8 (?): 856 PMID32984339show ga The COVID-19 pandemic is a global health crisis that requires the application of interdisciplinary research to address numerous knowledge gaps including molecular strategies to prevent viral reproduction in affected individuals. In response to the Frontiers Research Topic, "Coronavirus disease (COVID-19): Pathophysiology, Epidemiology, Clinical Management, and Public Health Response," this Hypothesis article proposes a novel therapeutic strategy to repurpose metabotropic glutamate 5 receptor (mGluR(5)) inhibitors to interfere with viral hijacking of the host protein synthesis machinery. We review pertinent background on SARS-CoV-2, fragile X syndrome (FXS) and metabotropic glutamate receptor 5 (mGluR(5)) and provide a mechanistic-based hypothesis and preliminary data to support testing mGluR(5) inhibitors in COVID-19 research. ?Repurposing Fragile X Drugs to Inhibit SARS-CoV-2 Viral Reproduction (epmc).pdf DeepDyve Pubget Overpricing