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10.1080/1354750X.2020.1829056 http://scihub22266oqcxt.onion/10.1080/1354750X.2020.1829056 32981387!7711742!32981387     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomarkers 2020 ; 25 (8): 626-633 Nephropedia Template TP {{tp|p=32981387|t=2020. High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19 |pdf=|usr=}}{{32981387}} gab.com Text High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19 JO: Biomarkers http://www.kidney.de/pget.php?&tw=1&pmid=32981387 #FOAvip BACKGROUND: High sensitivity cardiac troponin-T (hs-TnT) has been associated with mortality in patients hospitalized with COVID-19. We aimed to determine if hs-TnT levels and their timing are independent predictors of adverse events in these patients. DESIGN: Retrospective chart review was performed for all patients hospitalized at our institution between 23 March 2020 and 13 April 2020 who were found to be COVID-19-positive. Clinical, demographic, and laboratory variables including initial and peak hs-TnT were recorded. Univariable and multivariable analyses were completed for a primary composite endpoint of in-hospital death, intubation, need for critical care, or cardiac arrest. RESULTS: In the 276 patients analysed, initial hs-TnT above the median (>/=17 ng/L) was associated with increased length of stay, need for vasoactive medications, and death, along with the composite endpoint (OR 3.92, p < 0.001). Multivariable analysis demonstrated that elevated initial hs-TnT was independently associated with the primary endpoint (OR 2.92, p = 0.01). Late-peaking hs-TnT (OR 2.19 for each additional day until peak, p < 0.001) was also independently associated with the composite endpoint. CONCLUSIONS: In patients hospitalized with COVID-19, hs-TnT identifies patients at high risk for adverse in-hospital events, and trends of hs-TnT over time, particularly during the first day, provide additional prognostic information. Twit Text FOAVip High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19 ????Biomarkers http://www.kidney.de/pget.php?&tw=1&pmid=32981387 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32981387 #FOAvip English Wikipedia <ref>{{Cite pmid|32981387}}</ref> High sensitivity Troponin-T for prediction of adverse events in patients with COVID-19 #MMPMID32981387 Singh N; Anchan RK; Besser SA; Belkin MN; Cruz MD; Lee L; Yu D; Mehta N; Nguyen AB; Alenghat FJ Biomarkers 2020[Dec]; 25 (8): 626-633 PMID32981387show ga BACKGROUND: High sensitivity cardiac troponin-T (hs-TnT) has been associated with mortality in patients hospitalized with COVID-19. We aimed to determine if hs-TnT levels and their timing are independent predictors of adverse events in these patients. DESIGN: Retrospective chart review was performed for all patients hospitalized at our institution between 23 March 2020 and 13 April 2020 who were found to be COVID-19-positive. Clinical, demographic, and laboratory variables including initial and peak hs-TnT were recorded. Univariable and multivariable analyses were completed for a primary composite endpoint of in-hospital death, intubation, need for critical care, or cardiac arrest. RESULTS: In the 276 patients analysed, initial hs-TnT above the median (>/=17 ng/L) was associated with increased length of stay, need for vasoactive medications, and death, along with the composite endpoint (OR 3.92, p < 0.001). Multivariable analysis demonstrated that elevated initial hs-TnT was independently associated with the primary endpoint (OR 2.92, p = 0.01). Late-peaking hs-TnT (OR 2.19 for each additional day until peak, p < 0.001) was also independently associated with the composite endpoint. CONCLUSIONS: In patients hospitalized with COVID-19, hs-TnT identifies patients at high risk for adverse in-hospital events, and trends of hs-TnT over time, particularly during the first day, provide additional prognostic information. |Aged[MESH] |Aged, 80 and over[MESH] |Biomarkers/*blood[MESH] |COVID-19/*blood/epidemiology/virology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Predictive Value of Tests[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Assessment/methods/statistics & numerical data[MESH] |Risk Factors[MESH] |SARS-CoV-2/physiology[MESH] |Sensitivity and Specificity[MESH]High sensitivity Troponin-T for prediction of adverse events in patien(epmc).pdf DeepDyve Pubget Overpricing