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Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach #MMPMID32980860
Ueda Oshima M; Sandmaier BM; Petersdorf E; Flowers ME; Hill GR; Lee SJ; Appelbaum FR; Carpenter PA; Baker KS; Connelly-Smith L; McCool A; Elgar S; Pergam SA; Liu C; Stewart FM; Mielcarek M
Bone Marrow Transplant 2021[Feb]; 56 (2): 305-313 PMID32980860show ga
On January 20, 2020, the first patient with coronavirus disease 2019 (COVID-19) in the United States of America was diagnosed in Washington state, which subsequently experienced rapidly increasing numbers of COVID-19 cases, hospitalizations, and deaths. This placed the Seattle Blood and Marrow Transplant Program at Fred Hutchinson Cancer Research Center (Fred Hutch) in the national epicenter of this pandemic. Here, we summarize the experience gained during our rapid response to the COVID-19 pandemic. Our efforts were aimed at safely performing urgent and potentially life-saving stem cell transplants in the setting of pandemic-related stresses on healthcare resources and shelter-in-place public health measures. We describe the unique circumstances and challenges encountered, the current state of the program amidst evolving COVID-19 cases in our community, and the guiding principles for recovery. We also estimate the collateral impact of directing clinical resources toward COVID-19-related care on cancer patients in need of stem cell transplantation. Although our experience was influenced by specific regional and institutional factors, it may help inform how transplant programs respond to COVID-19 and future pandemics.
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Bone+Marrow+Transplant 2021 ; 56 (2): 305-313
