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10.1016/j.jviromet.2020.113978

http://scihub22266oqcxt.onion/10.1016/j.jviromet.2020.113978
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32979407!7510775!32979407
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suck abstract from ncbi


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pmid32979407      J+Virol+Methods 2021 ; 287 (ä): 113978
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  • Determination of SARS-CoV-2 antibodies with assays from Diasorin, Roche and IDvet #MMPMID32979407
  • Kruttgen A; Cornelissen CG; Dreher M; Hornef MW; Imohl M; Kleines M
  • J Virol Methods 2021[Jan]; 287 (ä): 113978 PMID32979407show ga
  • There is an ongoing need for highly reliable serological assays to detect individuals with past SARS-CoV-2 infection. Using 75 sera from patients tested positive or negative by SARS-CoV-2 PCR, we investigated the sensitivity and specificity of the Liaison SARS-CoV-2 S1/S2 IgG assay (DiaSorin), the Elecsys Anti-SARS-CoV-2 assay (Roche), and the ID Screen SARS-CoV-2-N IgG indirect kit (IDVet). We determined a sensitivity of 95.5 %, 95.5 %, and 100 % and a specificity of 90.5 %, 96.2 %, and 92.5 % for the DiaSorin assay, the Roche assay, and the IDVet assay, respectively. We conclude that serologic assays combining very high sensitivity and specificity are still not commercially available for SARS-CoV-2. For maximizing sensitivity and specificity of SARS-CoV-2 serological diagnostics, the combination of two assays may be helpful.
  • |Antibodies, Viral/blood[MESH]
  • |COVID-19 Serological Testing/*methods[MESH]
  • |COVID-19/*blood[MESH]
  • |Humans[MESH]
  • |Immunoassay[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |SARS-CoV-2/*immunology[MESH]


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