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10.1016/j.kint.2020.09.006

http://scihub22266oqcxt.onion/10.1016/j.kint.2020.09.006
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suck abstract from ncbi


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pmid32979369      Kidney+Int 2020 ; 98 (6): 1540-1548
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  • Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe #MMPMID32979369
  • Jager KJ; Kramer A; Chesnaye NC; Couchoud C; Sanchez-Alvarez JE; Garneata L; Collart F; Hemmelder MH; Ambuhl P; Kerschbaum J; Legeai C; Del Pino Y Pino MD; Mircescu G; Mazzoleni L; Hoekstra T; Winzeler R; Mayer G; Stel VS; Wanner C; Zoccali C; Massy ZA
  • Kidney Int 2020[Dec]; 98 (6): 1540-1548 PMID32979369show ga
  • The aim of this study was to investigate 28-day mortality after COVID-19 diagnosis in the European kidney replacement therapy population. In addition, we determined the role of patient characteristics, treatment factors, and country on mortality risk with the use of ERA-EDTA Registry data on patients receiving kidney replacement therapy in Europe from February 1, 2020, to April 30, 2020. Additional data on all patients with a diagnosis of COVID-19 were collected from 7 European countries encompassing 4298 patients. COVID-19-attributable mortality was calculated using propensity score-matched historic control data and after 28 days of follow-up was 20.0% (95% confidence interval 18.7%-21.4%) in 3285 patients receiving dialysis and 19.9% (17.5%-22.5%) in 1013 recipients of a transplant. We identified differences in COVID-19 mortality across countries, and an increased mortality risk in older patients receiving kidney replacement therapy and male patients receiving dialysis. In recipients of kidney transplants >/=75 years of age, 44.3% (35.7%-53.9%) did not survive COVID-19. Mortality risk was 1.28 (1.02-1.60) times higher in transplant recipients compared with matched dialysis patients. Thus, the pandemic has had a substantial effect on mortality in patients receiving kidney replacement therapy, a highly vulnerable population due to underlying chronic kidney disease and a high prevalence of multimorbidity.
  • |*Registries[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/complications/*mortality[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Europe/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Kidney Failure, Chronic/*complications/mortality/therapy[MESH]
  • |Kidney Transplantation/*mortality[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Postoperative Complications/*mortality/virology[MESH]
  • |Renal Dialysis[MESH]
  • |Risk Factors[MESH]


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