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10.1128/mBio.02134-20

http://scihub22266oqcxt.onion/10.1128/mBio.02134-20
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32978312!7520600!32978312
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suck abstract from ncbi

pmid32978312      mBio 2020 ; 11 (5): ?
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  • Antiviral Drug Discovery To Address the COVID-19 Pandemic #MMPMID32978312
  • Richman DD
  • mBio 2020[Sep]; 11 (5): ? PMID32978312show ga
  • The magnitude of the morbidity and mortality inflicted upon the global population in less than 1 year has driven the inescapable conclusion that the discovery and development of effective antiviral drugs for COVID-19 are urgent and should be prioritized. The antiviral drug discovery programs that emerged for HIV and hepatitis C virus have enabled technology and expertise to accelerate this process for SARS-CoV-2. The description of candidate lead inhibitors for the viral main protease (M(pro)) exemplifies this accelerated approach and reminds us of the needs and opportunities for addressing this pandemic.
  • |*Antiviral Agents[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral[MESH]
  • |*Severe Acute Respiratory Syndrome[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Cysteine Endopeptidases[MESH]
  • |Drug Discovery[MESH]
  • |Humans[MESH]
  • |Indoles[MESH]
  • |SARS-CoV-2[MESH]


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