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10.1177/1535370220962043 http://scihub22266oqcxt.onion/10.1177/1535370220962043 32972235!7797996!32972235     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Exp+Biol+Med+(Maywood) 2021 ; 246 (1): 5-9 Nephropedia Template TP {{tp|p=32972235|t=2021. Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients |pdf=|usr=}}{{32972235}} gab.com Text Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients JO: Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=32972235 #FOAvip Severe COVID-19 associated pneumonia and acute respiratory distress syndrome has recently been described with life-threatening features of cytokine storm and loosely referred to as hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS). Although a recent report indicated favorable responses to the interleukin-1 receptor antagonist, anakinra in eight patients with COVID-19 secondary HLH diagnosed using the HScore calculation, others have suggested that the diagnosis of secondary HLH is uncommon and that the use of the HScore has limited value in guiding immunomodulatory therapy for COVID-19. Here, we provide additional perspective on this important controversy based upon comparisons between 14 COVID-19 cytokine storm patients and 10 secondary HLH patients seen immediately prior to the pandemic. We hypothesize that identification of HLH may relate to the severity or timing of cytokine release and suggest distinguishing between cytokine release syndrome and secondary HLH, reserving the latter term for cases fulfilling diagnostic criteria. Twit Text FOAVip Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients ????Exp Biol Med (Maywood) http://www.kidney.de/pget.php?&tw=1&pmid=32972235 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32972235 #FOAvip English Wikipedia <ref>{{Cite pmid|32972235}}</ref> Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients #MMPMID32972235 Hakim NN; Chi J; Olazagasti C; Liu JM Exp Biol Med (Maywood) 2021[Jan]; 246 (1): 5-9 PMID32972235show ga Severe COVID-19 associated pneumonia and acute respiratory distress syndrome has recently been described with life-threatening features of cytokine storm and loosely referred to as hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS). Although a recent report indicated favorable responses to the interleukin-1 receptor antagonist, anakinra in eight patients with COVID-19 secondary HLH diagnosed using the HScore calculation, others have suggested that the diagnosis of secondary HLH is uncommon and that the use of the HScore has limited value in guiding immunomodulatory therapy for COVID-19. Here, we provide additional perspective on this important controversy based upon comparisons between 14 COVID-19 cytokine storm patients and 10 secondary HLH patients seen immediately prior to the pandemic. We hypothesize that identification of HLH may relate to the severity or timing of cytokine release and suggest distinguishing between cytokine release syndrome and secondary HLH, reserving the latter term for cases fulfilling diagnostic criteria. |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |COVID-19/*complications[MESH] |Cytokine Release Syndrome/*etiology[MESH] |Female[MESH] |Humans[MESH] |Lymphohistiocytosis, Hemophagocytic/*etiology/virology[MESH] |Male[MESH] |Middle Aged[MESH]Secondary hemophagocytic lymphohistiocytosis versus cytokine release s(epmc).pdf DeepDyve Pubget Overpricing