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10.3904/kjim.2020.325

http://scihub22266oqcxt.onion/10.3904/kjim.2020.325
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32972123!7820639!32972123
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suck abstract from ncbi


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pmid32972123      Korean+J+Intern+Med 2021 ; 36 (1): 11-14
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  • Dynamics of viral load and anti-SARS-CoV-2 antibodies in patients with positive RT-PCR results after recovery from COVID-19 #MMPMID32972123
  • Song KH; Kim DM; Lee H; Ham SY; Oh SM; Jeong H; Jung J; Kang CK; Park JY; Kang YM; Kim JY; Park JS; Park KU; Kim ES; Kim HB
  • Korean J Intern Med 2021[Jan]; 36 (1): 11-14 PMID32972123show ga
  • Recently, the number of patients with coronavirus disease 2019 (COVID-19) who have tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), via the reverse transcription polymerase chain reaction (RT-PCR) test, after recovery has increased; this has caused a dilemma regarding the medical measures and policies. We evaluated the dynamics of viral load and anti-SARS-CoV-2 antibodies in four patients with positive RT-PCR results after recovery. In all patients, the highest levels of immunoglobulin G (IgG) and IgM antibodies were reached after about a month of the onset of the initial symptoms. Then, the IgG titers plateaued, and the IgM titers decreased, regardless of RT-PCR results. The IgG and IgM levels did not increase after the post-negative positive RT-PCR results in any of the patients. Our results reinforced that the post-negative positive RT-PCR results may be due to the detection of RNA particles rather than reinfection in individuals who have recovered from COVID-19.
  • |*COVID-19 Nucleic Acid Testing[MESH]
  • |*COVID-19 Serological Testing[MESH]
  • |*Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |*Viral Load[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |Biomarkers/blood[MESH]
  • |COVID-19/blood/*diagnosis/virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Kinetics[MESH]
  • |Male[MESH]
  • |Predictive Value of Tests[MESH]
  • |RNA, Viral/*blood[MESH]
  • |Reinfection[MESH]
  • |Reproducibility of Results[MESH]
  • |Retrospective Studies[MESH]


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