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10.1016/j.jaip.2020.08.064

http://scihub22266oqcxt.onion/10.1016/j.jaip.2020.08.064
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32971311!7503132!32971311
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suck abstract from ncbi


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pmid32971311      J+Allergy+Clin+Immunol+Pract 2020 ; 8 (10): 3247-3250
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  • SARS-CoV-2 Pandemic Impacts on NASA Ground Operations to Protect ISS Astronauts #MMPMID32971311
  • Makedonas G; Mehta SK; Scheuring RA; Haddon R; Crucian BE
  • J Allergy Clin Immunol Pract 2020[Nov]; 8 (10): 3247-3250 PMID32971311show ga
  • NASA implements required medical tests and clinical monitoring to ensure the health and safety of its astronauts. These measures include a pre-launch quarantine to mitigate the risk of infectious diseases. During space missions, most astronauts experience perturbations to their immune system that manifest as a detectable secondary immunodeficiency. On return to Earth, after the stress of re-entry and landing, astronauts would be most vulnerable to infectious disease. In April 2020, a crew returned from International Space Station to NASA Johnson Space Center in Houston, Texas, during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Post-flight quarantine protocols (both crew and contacts) were enhanced to protect this crew from SARS-CoV-2. In addition, specific additional clinical monitoring was performed to determine post-flight immunocompetence. Given that coronavirus disease 2019 (COVID-19) prognosis is more severe for the immunocompromised, a countermeasures protocol for spaceflight suggested by an international team of scientists could benefit terrestrial patients with secondary immunodeficiency.
  • |*Astronauts[MESH]
  • |*Space Flight[MESH]
  • |Betacoronavirus[MESH]
  • |CD4 Lymphocyte Count[MESH]
  • |CD4-Positive T-Lymphocytes/immunology[MESH]
  • |CD8-Positive T-Lymphocytes/immunology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/immunology/*prevention & control[MESH]
  • |Dietary Supplements[MESH]
  • |Exercise Therapy[MESH]
  • |Granulocyte Colony-Stimulating Factor/therapeutic use[MESH]
  • |Humans[MESH]
  • |Immunocompromised Host/*immunology[MESH]
  • |Immunoglobulin G/therapeutic use[MESH]
  • |Interleukin-2/therapeutic use[MESH]
  • |Organizational Policy[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/immunology/*prevention & control[MESH]
  • |Quarantine/*methods/organization & administration[MESH]
  • |SARS-CoV-2[MESH]
  • |Spacecraft[MESH]
  • |Stress, Physiological/*immunology[MESH]
  • |Texas[MESH]
  • |United States[MESH]


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