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10.1371/journal.pone.0239801

http://scihub22266oqcxt.onion/10.1371/journal.pone.0239801
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32970774!7514100!32970774
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suck abstract from ncbi


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pmid32970774      PLoS+One 2020 ; 15 (9): e0239801
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  • Complications and mortality of cardiovascular emergency admissions during COVID-19 associated restrictive measures #MMPMID32970774
  • Bugger H; Gollmer J; Pregartner G; Wunsch G; Berghold A; Zirlik A; von Lewinski D
  • PLoS One 2020[]; 15 (9): e0239801 PMID32970774show ga
  • While hospital admissions for myocardial infarction (MI) and pulmonary embolism (PE) are decreased during the COVID-19 pandemic, controversy remains about respective complication and mortality rates. This study evaluated admission rates, complications, and intrahospital mortality for selected life-threatening cardiovascular emergencies (MI, PE, and acute aortic dissection (AAD)) during COVID-19-associated restrictive social measures (RM) in Styria, Austria. By screening a patient information system for International Statistical Classification of Diseases and Related Health Problems (ICD) diagnosis codes covering more than 85% of acute hospital admissions in the state of Styria (~1.24 million inhabitants), we retrospectively identified patients with admission diagnoses for MI (I21, I22), PE (I26), and AAD (I71). Rates of complications such as cardiogenic shock and cardiopulmonary resuscitation, treatment escalations (thrombolysis for PE), and mortality were analyzed by patient chart review during 6 weeks following onset of COVID-19 associated RM, and during respective time frames in the years 2016 to 2019. 1,668 patients were included. Cumulative admissions for MI, PE and AAD decreased (RR 0.77; p<0.001) during RM compared to previous years. In contrast, intrahospital mortality increased by 65% (RR 1.65; p = 0.041), mainly driven by mortality following MI (RR 1.80; p = 0.042). PE patients received more frequently thrombolysis treatment (RR 3.63; p = 0.006), while rates of cardiogenic shock and cardiopulmonary resuscitation remained unchanged. Of 226 patients hospitalized during RM, 81 patients with suspected COVID-19 disease were screened for SARS-CoV-2 infection with only 5 testing positive. Thus, cumulative hospital admissions for cardiovascular emergencies decreased during COVID-19 associated RM while intrahospital mortality increased.
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Aortic Dissection/*mortality[MESH]
  • |Austria[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Emergency Service, Hospital/*statistics & numerical data/trends[MESH]
  • |Female[MESH]
  • |Hospital Mortality/trends[MESH]
  • |Hospitalization/*statistics & numerical data/trends[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Myocardial Infarction/*mortality[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |Pulmonary Embolism/*mortality[MESH]
  • |Retrospective Studies[MESH]


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