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10.33314/jnhrc.v18i2.2806

http://scihub22266oqcxt.onion/10.33314/jnhrc.v18i2.2806
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32969369!ä!32969369

suck abstract from ncbi


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pmid32969369      J+Nepal+Health+Res+Counc 2020 ; 18 (2): 151-158
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  • Safety and Efficacy of Different Therapeutic Interventions on Prevention and Treatment of COVID-19 #MMPMID32969369
  • Gyanwali P; Sharma S; Pant S; Koirala P; Adhikari K; Koirala J; Dhimal M
  • J Nepal Health Res Counc 2020[Sep]; 18 (2): 151-158 PMID32969369show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the strain of coronavirus that causes coronavirus disease 2019 (COVID-19), a respiratory illness. COVID-19 has now become a global public health crisis causing alarming numbers of morbidity and mortality. Ever since the COVID-19 pandemic started scientists, researchers, universities, companies, and institutions all around the world have been endeavoring to discover a potential treatment for COVID-19. Numerous studies and clinical trials on vaccines and drugs for the prevention and treatment of COVID-19 are underway across the world. However, the uncertainty around the efficacy and safety of various treatment regimens have become one of the biggest challenges in the battle against the SARS-CoV-2. This paper is a narrative review of articles regarding the various treatments and vaccines being tested for the SARS-CoV-2, available in the PubMed database along with Google Scholar. There are ongoing clinical trials on potential drugs such as remdesivir, favipiravir, lopinavir/ritonavir, chloroquine, and hydroxychloroquine, corticosteroids tocilizumab, azithromycin, anakinra, etc. and other therapeutic modalities like convalescent plasma therapy. Likewise, vaccines against SARS-CoV-2 are being developed and tested, including mRNA, non-replicating viral vector, DNA, protein subunit candidate vaccines, etc. Although some early-stage clinical trials and studies on these drugs and vaccines have shown positive results, definitive and conclusive results are yet to be obtained. Keywords: COVID-19; antiviral drugs; COVID-19 treatment; COVID-19 vaccine; SARS-CoV-2.
  • |*Viral Vaccines[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Coronavirus Infections/drug therapy/prevention & control/*therapy[MESH]
  • |Humans[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Pneumonia, Viral/prevention & control/*therapy[MESH]


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