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10.26355/eurrev_202009_22867 http://scihub22266oqcxt.onion/10.26355/eurrev_202009_22867 32965010!ä!32965010 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+Rev+Med+Pharmacol+Sci 2020 ; 24 (17): 9169-9171 Nephropedia Template TP {{tp|p=32965010|t=2020. SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications?|pdf=|usr=}}{{32965010}} gab.com Text SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications JO: Eur Rev Med Pharmacol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32965010 #FOAvip NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome has recently become an intriguing target of several chronic and viral diseases. Here, we argue that targeting NLRP3 inflammasome could be a strategy to prevent cardiovascular outcomes [fulminant myocarditis, heart failure, venous thromboembolism (VTE)] and acute respiratory distress syndrome (ARDS) in patients with SARS-CoV-2 infection. We discuss the rationale for NLRP3 targeting in clinical trials as an effective therapeutic strategy aimed to improve prognosis of COVID-19, analyzing the potential of two therapeutic options (tranilast and OLT1177) currently available in clinical practice. Twit Text FOAVip SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications ????Eur Rev Med Pharmacol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32965010 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32965010 #FOAvip English Wikipedia <ref>{{Cite pmid|32965010}}</ref> SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications? #MMPMID32965010 Quagliariello V; Bonelli A; Caronna A; Lombari MC; Conforti G; Libutti M; Iaffaioli RV; Berretta M; Botti G; Maurea N Eur Rev Med Pharmacol Sci 2020[Sep]; 24 (17): 9169-9171 PMID32965010show ga NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome has recently become an intriguing target of several chronic and viral diseases. Here, we argue that targeting NLRP3 inflammasome could be a strategy to prevent cardiovascular outcomes [fulminant myocarditis, heart failure, venous thromboembolism (VTE)] and acute respiratory distress syndrome (ARDS) in patients with SARS-CoV-2 infection. We discuss the rationale for NLRP3 targeting in clinical trials as an effective therapeutic strategy aimed to improve prognosis of COVID-19, analyzing the potential of two therapeutic options (tranilast and OLT1177) currently available in clinical practice. |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |Cardiovascular Diseases/*prevention & control[MESH] |Clinical Trials as Topic[MESH] |Coronavirus Infections/*diagnosis/virology[MESH] |Cytokines/metabolism[MESH] |Humans[MESH] |Inflammasomes/metabolism[MESH] |Myocarditis/prevention & control[MESH] |NLR Family, Pyrin Domain-Containing 3 Protein/antagonists & inhibitors/*metabolism[MESH] |Nitriles/therapeutic use[MESH] |Pandemics[MESH] |Pneumonia, Viral/*diagnosis/virology[MESH] |Prognosis[MESH] |SARS-CoV-2[MESH] |Venous Thromboembolism/prevention & control[MESH]SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to preven(epmc).pdf DeepDyve Pubget Overpricing