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10.3390/v12091039 http://scihub22266oqcxt.onion/10.3390/v12091039 32961897!7551260!32961897     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32961897&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2020 ; 12 (9): ä Nephropedia Template TP {{tp|p=32961897|t=2020. Induction of the Antiviral Immune Response and Its Circumvention by Coronaviruses |pdf=|usr=}}{{32961897}} gab.com Text Induction of the Antiviral Immune Response and Its Circumvention by Coronaviruses JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32961897 #FOAvip Some coronaviruses are zoonotic viruses of human and veterinary medical importance. The novel coronavirus, severe acute respiratory symptoms coronavirus 2 (SARS-CoV-2), associated with the current global pandemic, is characterized by pneumonia, lymphopenia, and a cytokine storm in humans that has caused catastrophic impacts on public health worldwide. Coronaviruses are known for their ability to evade innate immune surveillance exerted by the host during the early phase of infection. It is important to comprehensively investigate the interaction between highly pathogenic coronaviruses and their hosts. In this review, we summarize the existing knowledge about coronaviruses with a focus on antiviral immune responses in the respiratory and intestinal tracts to infection with severe coronaviruses that have caused epidemic diseases in humans and domestic animals. We emphasize, in particular, the strategies used by these coronaviruses to circumvent host immune surveillance, mainly including the hijack of antigen-presenting cells, shielding RNA intermediates in replication organelles, 2'-O-methylation modification for the evasion of RNA sensors, and blocking of interferon signaling cascades. We also provide information about the potential development of coronavirus vaccines and antiviral drugs. Twit Text FOAVip Induction of the Antiviral Immune Response and Its Circumvention by Coronaviruses ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=32961897 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32961897 #FOAvip English Wikipedia <ref>{{Cite pmid|32961897}}</ref> Induction of the Antiviral Immune Response and Its Circumvention by Coronaviruses #MMPMID32961897 Liu P; Hong Y; Yang B; Shrestha P; Sajjad N; Chen JL Viruses 2020[Sep]; 12 (9): ä PMID32961897show ga Some coronaviruses are zoonotic viruses of human and veterinary medical importance. The novel coronavirus, severe acute respiratory symptoms coronavirus 2 (SARS-CoV-2), associated with the current global pandemic, is characterized by pneumonia, lymphopenia, and a cytokine storm in humans that has caused catastrophic impacts on public health worldwide. Coronaviruses are known for their ability to evade innate immune surveillance exerted by the host during the early phase of infection. It is important to comprehensively investigate the interaction between highly pathogenic coronaviruses and their hosts. In this review, we summarize the existing knowledge about coronaviruses with a focus on antiviral immune responses in the respiratory and intestinal tracts to infection with severe coronaviruses that have caused epidemic diseases in humans and domestic animals. We emphasize, in particular, the strategies used by these coronaviruses to circumvent host immune surveillance, mainly including the hijack of antigen-presenting cells, shielding RNA intermediates in replication organelles, 2'-O-methylation modification for the evasion of RNA sensors, and blocking of interferon signaling cascades. We also provide information about the potential development of coronavirus vaccines and antiviral drugs. |*Immune Evasion[MESH] |Antiviral Agents/*immunology/therapeutic use[MESH] |Betacoronavirus/immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/drug therapy/immunology/*virology[MESH] |Coronavirus/classification/*immunology/physiology[MESH] |Cytokines/immunology[MESH] |Immunity, Innate[MESH] |Immunity, Mucosal[MESH] |Pandemics[MESH] |Pneumonia, Viral/drug therapy/immunology/*virology[MESH] |SARS-CoV-2[MESH] |Signal Transduction[MESH]Induction of the Antiviral Immune Response and Its Circumvention by C(epmc).pdf DeepDyve Pubget Overpricing