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10.1016/j.ejphar.2020.173568

http://scihub22266oqcxt.onion/10.1016/j.ejphar.2020.173568
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suck abstract from ncbi


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pmid32956644      Eur+J+Pharmacol 2020 ; 887 (ä): 173568
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  • A review of medications used to control and improve the signs and symptoms of COVID-19 patients #MMPMID32956644
  • Hushmandi K; Bokaie S; Hashemi M; Moghadam ER; Raei M; Hashemi F; Bagheri M; Habtemariam S; Nabavi SM
  • Eur J Pharmacol 2020[Nov]; 887 (ä): 173568 PMID32956644show ga
  • In December 2019, an unprecedented outbreak of pneumonia associated with a novel coronavirus disease 2019 (COVID-19) emerged in Wuhan City, Hubei province, China. The virus that caused the disease was officially named by the World Health Organization (WHO) as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). According to the high transmission rate of SARS-CoV-2, it became a global pandemic and public health emergency within few months. Since SARS-CoV-2 is genetically 80% homologous with the SARS-CoVs family, it is hypothesized that medications developed for the treatment of SARS-CoVs may be useful in the control and management of SARS-CoV-2. In this regard, some medication being tested in clinical trials and in vitro studies include anti-viral RNA polymerase inhibitors, HIV-protease inhibitors, anti-inflammatory agents, angiotensin converting enzyme type 2 (ACE 2) blockers, and some other novel medications. In this communication, we reviewed the general characteristics of medications, medical usage, mechanism of action, as well as SARS-CoV-2 related trials.
  • |Anti-Inflammatory Agents/pharmacology/therapeutic use[MESH]
  • |Antiviral Agents/pharmacology/therapeutic use[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Chloroquine/analogs & derivatives/therapeutic use[MESH]
  • |Coronavirus Infections/*drug therapy/*physiopathology[MESH]
  • |DNA-Directed RNA Polymerases/antagonists & inhibitors[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]


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