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10.5144/0256-4947.2020.365

http://scihub22266oqcxt.onion/10.5144/0256-4947.2020.365
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suck abstract from ncbi

pmid32954790      Ann+Saudi+Med 2020 ; 40 (5): 365-372
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  • Saudi Heart Rhythm Society Task Force on Management of Potential Arrhythmogenicity Associated with Pharmacotherapy for COVID-19 #MMPMID32954790
  • AlShoaibi NA; Maghrabi K; Alanazi H; Harbi MA; Alghamdi S
  • Ann Saudi Med 2020[Sep]; 40 (5): 365-372 PMID32954790show ga
  • Evidence of cardiovascular complications associated with the COVID-19 global pandemic continues to evolve. These include direct and indirect myocardial injury with subsequent acute myocardial ischemia, and cardiac arrhythmia. Some results from a limited number of trials of antiviral medications, along with chloroquine/hydroxychloroquine and azithromycin, have been beneficial. However, these pharmacotherapies may cause drug-induced QT prolongation leading to ventricular arrhythmias and sudden cardiac death. Mitigation of the potential risk in these susceptible patients may prove exceptionally challenging. The Saudi Heart Rhythm Society established a task force to perform a review of this subject based on has recently published reports, and studies and recommendations from major medical organizations. The objective of this review is to identify high-risk patients, and to set clear guidelines for management of patients receiving these pharmacotherapies.
  • |Adrenergic beta-Antagonists/therapeutic use[MESH]
  • |Advisory Committees[MESH]
  • |Antiviral Agents/adverse effects[MESH]
  • |Arrhythmias, Cardiac/*chemically induced/diagnosis[MESH]
  • |Azithromycin/adverse effects[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Chloroquine/adverse effects[MESH]
  • |Coronavirus Infections/*drug therapy[MESH]
  • |Cytochrome P-450 CYP2D6 Inhibitors/adverse effects[MESH]
  • |Drug Combinations[MESH]
  • |Drug Interactions[MESH]
  • |Drug Monitoring[MESH]
  • |Electrocardiography[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/adverse effects[MESH]
  • |Long QT Syndrome/chemically induced/diagnosis[MESH]
  • |Lopinavir/adverse effects[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy[MESH]
  • |Risk Assessment[MESH]
  • |Ritonavir/adverse effects[MESH]
  • |SARS-CoV-2[MESH]
  • |Saudi Arabia[MESH]


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