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10.21037/tlcr-20-892 http://scihub22266oqcxt.onion/10.21037/tlcr-20-892 32953523!7481645!32953523     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32953523&cmd=llinks): Failed to open stream: HTTP request failed! 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COVID-19 and early-stage lung cancer both featuring ground-glass opacities: a propensity score-matched study |pdf=|usr=}}{{32953523}} gab.com Text COVID-19 and early-stage lung cancer both featuring ground-glass opacities: a propensity score-matched study JO: Transl Lung Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=32953523 #FOAvip BACKGROUND: Radiological manifestations of coronavirus disease 2019 (COVID-19) featured ground-glass opacities (GGOs), especially in the early stage, which might create confusion in differential diagnosis with early lung cancer. We aimed to specify the radiological characteristics of COVID-19 and early lung cancer and to unveil the discrepancy between them. METHODS: One hundred and fifty-seven COVID-19 patients and 374 early lung cancer patients from four hospitals in China were retrospectively enrolled. Epidemiological, clinical, radiological, and pathological characteristics were compared between the two groups using propensity score-matched (PSM) analysis. RESULTS: COVID-19 patients had more distinct symptoms, tended to be younger (P<0.0001), male (P<0.0001), and had a higher body mass index (P=0.014). After 1:1 PSM, 121 matched pairs were identified. Regarding radiological characteristics, patients with a single lesion accounted for 17% in COVID-19 and 89% in lung cancer (P<0.0001). Most lesions were peripherally found in both groups. Lesions in COVID-19 involved more lobes (median 3.5 vs. 1; P<0.0001) and segments (median 6 vs. 1; P<0.0001) and tended to have multiple types (67%) with patchy form (54%). Early lung cancer was more likely to have a single type (92%) with oval form (66%). Also, COVID-19 and early lung cancer either had some distinctive features on computed tomography (CT) images. CONCLUSIONS: Both COVID-19 and early lung cancers showed GGOs, with similar but independent features. The imaging characteristics should be fully understood and combined with epidemiological history, pathogen detection, laboratory tests, short-term CT reexamination, and pathological results to aid differential diagnosis. Twit Text FOAVip COVID-19 and early-stage lung cancer both featuring ground-glass opacities: a propensity score-matched study ????Transl Lung Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=32953523 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32953523 #FOAvip English Wikipedia <ref>{{Cite pmid|32953523}}</ref> COVID-19 and early-stage lung cancer both featuring ground-glass opacities: a propensity score-matched study #MMPMID32953523 Zhang YJ; Yang WJ; Liu D; Cao YQ; Zheng YY; Han YC; Jin RS; Han Y; Wang XY; Pan AS; Dai JY; Sun QF; Zhao FQ; Yang QY; Zhang JH; Liu SJ; Da Q; Guo W; Li CQ; Zhang WT; Wu H; Chen XS; Ji AQ; Xiang J; Chen K; Feng XJ; Zhang XF; Cao QQ; Qin L; Li J; Zhou M; Lu Y; Wang CF; Yan FH; Li HC; Qu JM Transl Lung Cancer Res 2020[Aug]; 9 (4): 1516-1527 PMID32953523show ga BACKGROUND: Radiological manifestations of coronavirus disease 2019 (COVID-19) featured ground-glass opacities (GGOs), especially in the early stage, which might create confusion in differential diagnosis with early lung cancer. We aimed to specify the radiological characteristics of COVID-19 and early lung cancer and to unveil the discrepancy between them. METHODS: One hundred and fifty-seven COVID-19 patients and 374 early lung cancer patients from four hospitals in China were retrospectively enrolled. Epidemiological, clinical, radiological, and pathological characteristics were compared between the two groups using propensity score-matched (PSM) analysis. RESULTS: COVID-19 patients had more distinct symptoms, tended to be younger (P<0.0001), male (P<0.0001), and had a higher body mass index (P=0.014). After 1:1 PSM, 121 matched pairs were identified. Regarding radiological characteristics, patients with a single lesion accounted for 17% in COVID-19 and 89% in lung cancer (P<0.0001). Most lesions were peripherally found in both groups. Lesions in COVID-19 involved more lobes (median 3.5 vs. 1; P<0.0001) and segments (median 6 vs. 1; P<0.0001) and tended to have multiple types (67%) with patchy form (54%). Early lung cancer was more likely to have a single type (92%) with oval form (66%). Also, COVID-19 and early lung cancer either had some distinctive features on computed tomography (CT) images. CONCLUSIONS: Both COVID-19 and early lung cancers showed GGOs, with similar but independent features. The imaging characteristics should be fully understood and combined with epidemiological history, pathogen detection, laboratory tests, short-term CT reexamination, and pathological results to aid differential diagnosis. äCOVID-19 and early-stage lung cancer both featuring ground-glass opaci(epmc).pdf DeepDyve Pubget Overpricing