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10.1007/s40267-020-00777-z

http://scihub22266oqcxt.onion/10.1007/s40267-020-00777-z
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32952393!7487439!32952393
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suck abstract from ncbi


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pmid32952393      Drugs+Ther+Perspect 2020 ; 36 (12): 568-572
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  • Severe prolonged neutropenia following administration of tocilizumab in a patient affected by COVID-19: a case report and brief review of the literature #MMPMID32952393
  • Bernardo L; Del Sesto S; Giordano L; Benincaso AR; Biondi P; Goj V; Ferrara F; Talenti A; Grisolia A; Ascierto PA
  • Drugs Ther Perspect 2020[]; 36 (12): 568-572 PMID32952393show ga
  • Tocilizumab is one of the newest therapeutic options for the acute respiratory distress syndrome (ARDS) caused by the recently discovered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) beta-coronavirus. Several trials are currently ongoing to assess the efficacy and safety profile of tocilizumab in treating ARDS. In this article, we present the case of a Black patient with acute pneumonia who benefited greatly from tocilizumab, but developed severe prolonged neutropenia. Considering the increasing use of tocilizumab among patients with coronavirus disease 2019 (COVID-19), this case warrants further research regarding the possible adverse hematological effects that need to be monitored in order to prevent secondary infections.
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