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suck abstract from ncbi


10.1111/nep.13786

http://scihub22266oqcxt.onion/10.1111/nep.13786
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32951300!7536982!32951300
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suck abstract from ncbi

pmid32951300      Nephrology+(Carlton) 2020 ; 25 (12): 933-936
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  • Case of "relapsing" COVID-19 in a kidney transplant recipient #MMPMID32951300
  • Ma BM; Hung IFN; Chan GCW; Tam AR; Chan SSK; Wong BCK; Fukuda K; Ohno T; Yuen KY; Chan TM
  • Nephrology (Carlton) 2020[Dec]; 25 (12): 933-936 PMID32951300show ga
  • Clinical outcomes of COVID-19 vary considerably between patients. Little was known about the clinical course and optimal management of immunosuppressed patients infected with SARS-CoV-2. We report a kidney transplant recipient with COVID-19 who presented with pneumonitis and acute kidney injury (AKI). She improved after reduction of immunosuppressive treatment and had two consecutive negative reverse transcription polymerase chain reaction (RT-PCR) tests. Her respiratory tract samples turned positive again afterwards, and she was treated with lopinavir-ritonavir. She had satisfactory virological and clinical response after a prolonged disease course. This case illustrates the risk of relapse or persisting shedding of SARS-CoV-2 in immunosuppressed patients, the important role of viral load monitoring in management, the challenges in balancing the risks of COVID-19 progression and transplant rejection, and the pharmacokinetic interaction between immunosuppressive and antiviral medications.
  • |*Kidney Transplantation[MESH]
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19/*complications/immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]


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