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10.1016/j.clinph.2020.08.003

http://scihub22266oqcxt.onion/10.1016/j.clinph.2020.08.003
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suck abstract from ncbi

pmid32949985      Clin+Neurophysiol 2020 ; 131 (11): 2651-2656
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  • Continuous electroencephalography characteristics and acute symptomatic seizures in COVID-19 patients #MMPMID32949985
  • Louis S; Dhawan A; Newey C; Nair D; Jehi L; Hantus S; Punia V
  • Clin Neurophysiol 2020[Nov]; 131 (11): 2651-2656 PMID32949985show ga
  • OBJECTIVE: As concerns regarding neurological manifestations in COVID-19 (coronavirus disease 2019) patients increase, limited data exists on continuous electroencephalography (cEEG) findings in these patients. We present a retrospective cohort study of cEEG monitoring in COVID-19 patients to better explore this knowledge gap. METHODS: Among 22 COVID-19 patients, 19 underwent cEEGs, and 3 underwent routine EEGs (<1 h). Demographic and clinical variables, including comorbid conditions, discharge disposition, survival and cEEG findings, were collected. RESULTS: cEEG was performed for evaluation of altered mental status (n = 17) or seizure-like events (n = 5). Five patients, including 2 with epilepsy, had epileptiform abnormalities on cEEG. Two patients had electrographic seizures without a prior epilepsy history. There were no acute neuroimaging findings. Periodic discharges were noted in one-third of patients and encephalopathic EEG findings were not associated with IV anesthetic use. CONCLUSIONS: Interictal epileptiform abnormalities in the absence of prior epilepsy history were rare. However, the discovery of asymptomatic seizures in two of twenty-two patients was higher than previously reported and is therefore of concern. SIGNIFICANCE: cEEG monitoring in COVID-19 patients may aid in better understanding an epileptogenic potential of SARS-CoV2 infection. Nevertheless, larger studies utilizing cEEG are required to better examine acute epileptic risk in COVID-19 patients.
  • |Aged[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/diagnosis/*physiopathology[MESH]
  • |Electroencephalography/*methods[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Neurophysiological Monitoring/*methods[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/complications/diagnosis/*physiopathology[MESH]


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