Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1126/sciadv.abd3916 http://scihub22266oqcxt.onion/10.1126/sciadv.abd3916 32948512!7556756!32948512     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Adv 2020 ; 6 (42): ä Nephropedia Template TP {{tp|p=32948512|t=2020. Antibody-like proteins that capture and neutralize SARS-CoV-2 |pdf=|usr=}}{{32948512}} gab.com Text Antibody-like proteins that capture and neutralize SARS-CoV-2 JO: Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=32948512 #FOAvip To combat severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and any unknown emerging pathogens in the future, the development of a rapid and effective method to generate high-affinity antibodies or antibody-like proteins is of critical importance. We here report high-speed in vitro selection of multiple high-affinity antibody-like proteins against various targets including the SARS-CoV-2 spike protein. The sequences of monobodies against the SARS-CoV-2 spike protein were successfully procured within only 4 days. Furthermore, the obtained monobody efficiently captured SARS-CoV-2 particles from the nasal swab samples of patients and exhibited a high neutralizing activity against SARS-CoV-2 infection (half-maximal inhibitory concentration, 0.5 nanomolar). High-speed in vitro selection of antibody-like proteins is a promising method for rapid development of a detection method for, and of a neutralizing protein against, a virus responsible for an ongoing, and possibly a future, pandemic. Twit Text FOAVip Antibody-like proteins that capture and neutralize SARS-CoV-2 ????Sci Adv http://www.kidney.de/pget.php?&tw=1&pmid=32948512 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32948512 #FOAvip English Wikipedia <ref>{{Cite pmid|32948512}}</ref> Antibody-like proteins that capture and neutralize SARS-CoV-2 #MMPMID32948512 Kondo T; Iwatani Y; Matsuoka K; Fujino T; Umemoto S; Yokomaku Y; Ishizaki K; Kito S; Sezaki T; Hayashi G; Murakami H Sci Adv 2020[Oct]; 6 (42): ä PMID32948512show ga To combat severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and any unknown emerging pathogens in the future, the development of a rapid and effective method to generate high-affinity antibodies or antibody-like proteins is of critical importance. We here report high-speed in vitro selection of multiple high-affinity antibody-like proteins against various targets including the SARS-CoV-2 spike protein. The sequences of monobodies against the SARS-CoV-2 spike protein were successfully procured within only 4 days. Furthermore, the obtained monobody efficiently captured SARS-CoV-2 particles from the nasal swab samples of patients and exhibited a high neutralizing activity against SARS-CoV-2 infection (half-maximal inhibitory concentration, 0.5 nanomolar). High-speed in vitro selection of antibody-like proteins is a promising method for rapid development of a detection method for, and of a neutralizing protein against, a virus responsible for an ongoing, and possibly a future, pandemic. |Amino Acid Sequence[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Antibodies, Immobilized/chemistry/immunology[MESH] |Antibodies, Neutralizing/chemistry/immunology/metabolism[MESH] |Betacoronavirus/genetics/*immunology/isolation & purification[MESH] |COVID-19[MESH] |Cell Surface Display Techniques/methods[MESH] |Coronavirus Infections/pathology/virology[MESH] |Dimerization[MESH] |Humans[MESH] |Kinetics[MESH] |Pandemics[MESH] |Peptides/chemistry/immunology[MESH] |Peptidyl-Dipeptidase A/chemistry/*immunology/metabolism[MESH] |Pneumonia, Viral/pathology/virology[MESH] |Protein Domains/immunology[MESH] |Protein Subunits/chemistry/immunology/metabolism[MESH] |RNA, Viral/metabolism[MESH] |SARS-CoV-2[MESH] |Single-Domain Antibodies/chemistry/*immunology/metabolism[MESH]Antibody-like proteins that capture and neutralize SARS-CoV-2 (epmc).pdf DeepDyve Pubget Overpricing