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10.1002/jmv.26527

http://scihub22266oqcxt.onion/10.1002/jmv.26527
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32946118!7537084!32946118
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suck abstract from ncbi


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pmid32946118      J+Med+Virol 2021 ; 93 (3): 1665-1671
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  • Clinical laboratory characteristics in patients with suspected COVID-19: One single-institution experience #MMPMID32946118
  • Fei F; Smith JA; Cao L
  • J Med Virol 2021[Mar]; 93 (3): 1665-1671 PMID32946118show ga
  • OBJECTIVES: Since December 2019, the outbreak of coronavirus disease 2019 (COVID-19) has become a worldwide pandemic. The aim of the study is to investigate the demographic, clinical, and laboratory characteristics in suspected COVID-19 patients in our institution. METHODS: In this retrospective study, we investigated suspected COVID-19 patients admitted to the University of Alabama at Birmingham with a request for an interleukin-6 send-out test, from March 28 to June 27, 2020. Patients' demographic, clinical, and laboratory characteristics were collected by chart review. RESULTS: Fifty patients suspected with COVID-19 were included in our study, of whom 24 patients were positive with severe acute respiratory syndrome coronavirus-2 infection and 26 were negative. During the observation period, 30 patients were discharged, 17 died during hospitalization, and three remained in hospital. Compared to non-COVID-19 patients, COVID-19 patients had older age, more comorbidities, and elevated levels of inflammation markers such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serum ferritin, and lactate dehydrogenase (LDH). However, there was no significant difference in laboratory data between survivors and nonsurvivors in COVID-19 patients in our study. CONCLUSION: This study indicated that potential risk factors of older age, multiple comorbidities, and high levels of ESR, CRP, serum ferritin, and LDH could help the clinician to identify potential COVID-19 patients. However, this data needs to be further validated in a larger population.
  • |*Blood Sedimentation[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Aging[MESH]
  • |Biomarkers/blood[MESH]
  • |C-Reactive Protein/*analysis[MESH]
  • |COVID-19/*blood/diagnosis/pathology[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Ferritins/*blood[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Inflammation/blood[MESH]
  • |Interleukin-6/blood[MESH]
  • |L-Lactate Dehydrogenase/*blood[MESH]
  • |Length of Stay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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