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10.1038/s41591-020-1092-0

http://scihub22266oqcxt.onion/10.1038/s41591-020-1092-0
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32943787!ä!32943787

suck abstract from ncbi


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pmid32943787      Nat+Med 2020 ; 26 (11): 1714-1719
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  • Clustering and superspreading potential of SARS-CoV-2 infections in Hong Kong #MMPMID32943787
  • Adam DC; Wu P; Wong JY; Lau EHY; Tsang TK; Cauchemez S; Leung GM; Cowling BJ
  • Nat Med 2020[Nov]; 26 (11): 1714-1719 PMID32943787show ga
  • Superspreading events (SSEs) have characterized previous epidemics of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) infections(1-6). For SARS-CoV-2, the degree to which SSEs are involved in transmission remains unclear, but there is growing evidence that SSEs might be a typical feature of COVID-19(7,8). Using contact tracing data from 1,038 SARS-CoV-2 cases confirmed between 23 January and 28 April 2020 in Hong Kong, we identified and characterized all local clusters of infection. We identified 4-7 SSEs across 51 clusters (n = 309 cases) and estimated that 19% (95% confidence interval, 15-24%) of cases seeded 80% of all local transmission. Transmission in social settings was associated with more secondary cases than households when controlling for age (P = 0.002). Decreasing the delay between symptom onset and case confirmation did not result in fewer secondary cases (P = 0.98), although the odds that an individual being quarantined as a contact interrupted transmission was 14.4 (95% CI, 1.9-107.2). Public health authorities should focus on rapidly tracing and quarantining contacts, along with implementing restrictions targeting social settings to reduce the risk of SSEs and suppress SARS-CoV-2 transmission.
  • |COVID-19/*epidemiology/*transmission[MESH]
  • |Carrier State/epidemiology[MESH]
  • |Cluster Analysis[MESH]
  • |Contact Tracing[MESH]
  • |Female[MESH]
  • |Health Policy[MESH]
  • |Hong Kong/epidemiology[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Models, Theoretical[MESH]
  • |Pandemics[MESH]
  • |Patient Isolation/legislation & jurisprudence[MESH]
  • |Public Health/legislation & jurisprudence[MESH]
  • |Quarantine/legislation & jurisprudence[MESH]
  • |SARS-CoV-2/physiology[MESH]


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