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10.1177/0022034520960070

http://scihub22266oqcxt.onion/10.1177/0022034520960070
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32936047!ä!32936047

suck abstract from ncbi


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pmid32936047      J+Dent+Res 2020 ; 99 (13): 1435-1443
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  • Saliva in the Diagnosis of COVID-19: A Review and New Research Directions #MMPMID32936047
  • Fernandes LL; Pacheco VB; Borges L; Athwal HK; de Paula Eduardo F; Bezinelli L; Correa L; Jimenez M; Dame-Teixeira N; Lombaert IMA; Heller D
  • J Dent Res 2020[Dec]; 99 (13): 1435-1443 PMID32936047show ga
  • This review presents literature that highlights saliva's utility as a biofluid in the diagnosis and monitoring of COVID-19. A systematic search was performed in 5 electronic databases (PubMed, Embase, LILACS, Scopus, and Web of Science). Studies were eligible for inclusion if they assessed the potential diagnostic value and/or other discriminatory properties of biological markers in the saliva of patients with COVID-19. As of July 22, 2020, a total of 28 studies have investigated the presence of SARS-CoV-2 RNA in saliva. Several of those studies confirmed reliable detection of SARS-CoV-2 in the saliva of patients with COVID-19. Saliva offered sensitivity and specificity for SARS-CoV-2 detection comparable to that of the current standard of nasopharyngeal and throat swabs. However, the utility of saliva in diagnosing COVID-19 infection remains understudied. Clinical studies with larger patient populations that measure recordings at different stages during the disease are still necessary to confirm the accuracy of COVID-19 diagnosis with saliva. Nevertheless, the utility of saliva as a diagnostic tool opens the possibility of using rapid and less invasive diagnostic strategies by targeting bioanalytes rather than the pathogen.
  • |COVID-19/*diagnosis[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Humans[MESH]
  • |RNA, Viral/isolation & purification[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]


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