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10.3967/bes2020.080

http://scihub22266oqcxt.onion/10.3967/bes2020.080
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32933613!7505108!32933613
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suck abstract from ncbi


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pmid32933613      Biomed+Environ+Sci 2020 ; 33 (8): 614-619
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  • Coronavirus Disease 2019 versus Influenza A in Children: An Observational Control Study in China #MMPMID32933613
  • Zhao Y; Sun L; Bouchard HC; Zhang XX; Wan G; Hao YW; He SX; Jiang YY; Pang L
  • Biomed Environ Sci 2020[Aug]; 33 (8): 614-619 PMID32933613show ga
  • This study aimed to understand the differences in clinical, epidemiological, and laboratory features between the new coronavirus disease 2019 (COVID-2019) and influenza A in children. Data of 23 hospitalized children with COVID-19 (9 boys, 5.7 +/- 3.8 years old) were compared with age- and sex-matched 69 hospitalized and 69 outpatient children with influenza A from a hospital in China. The participants' epidemiological history, family cluster, clinical manifestations, and blood test results were assessed. Compared with either inpatients or outpatients with influenza A, children with COVID-19 showed significantly more frequent family infections and higher ratio of low fever (< 37.3 degrees C), but shorter cough and fever duration, lower body temperature, and lower rates of cough, fever, high fever (> 39 degrees C), nasal congestion, rhinorrhea, sore throat, vomiting, myalgia or arthralgia, and febrile seizures. They also showed higher counts of lymphocytes, T lymphocyte CD8, and platelets and levels of cholinesterase, aspartate aminotransferase, lactate dehydrogenase, and lactic acid, but lower serum amyloid, C-reactive protein, and fibrinogen levels and erythrocyte sedimentation rate, and shorter prothrombin time. The level of alanine aminotransferase in children with COVID-19 is lower than that in inpatients but higher than that in outpatients with influenza A. Pediatric COVID-19 is associated with more frequent family infection, milder symptoms, and milder immune responses relative to pediatric influenza A.
  • |Betacoronavirus/*physiology[MESH]
  • |COVID-19[MESH]
  • |Case-Control Studies[MESH]
  • |Child[MESH]
  • |Coronavirus Infections/blood/*epidemiology/immunology/*virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Influenza, Human/blood/*epidemiology/immunology[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/blood/*epidemiology/immunology/*virology[MESH]


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