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10.2196/21915

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32931444!7528732!32931444
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suck abstract from ncbi


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pmid32931444      J+Med+Internet+Res 2020 ; 22 (9): e21915
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  • Effects of the COVID-19 Pandemic on Obsessive-Compulsive Symptoms Among University Students: Prospective Cohort Survey Study #MMPMID32931444
  • Ji G; Wei W; Yue KC; Li H; Shi LJ; Ma JD; He CY; Zhou SS; Zhao Z; Lou T; Cheng J; Yang SC; Hu XZ
  • J Med Internet Res 2020[Sep]; 22 (9): e21915 PMID32931444show ga
  • BACKGROUND: The COVID-19 pandemic is associated with common mental health problems. However, evidence for the association between fear of COVID-19 and obsessive-compulsive disorder (OCD) is limited. OBJECTIVE: This study aimed to examine if fear of negative events affects Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) scores in the context of a COVID-19-fear-invoking environment. METHODS: All participants were medical university students and voluntarily completed three surveys via smartphone or computer. Survey 1 was conducted on February 8, 2020, following a 2-week-long quarantine period without classes; survey 2 was conducted on March 25, 2020, when participants had been taking online courses for 2 weeks; and survey 3 was conducted on April 28, 2020, when no new cases had been reported for 2 weeks. The surveys comprised the Y-BOCS and the Zung Self-Rating Anxiety Scale (SAS); additional items included questions on demographics (age, gender, only child vs siblings, enrollment year, major), knowledge of COVID-19, and level of fear pertaining to COVID-19. RESULTS: In survey 1, 11.3% of participants (1519/13,478) scored >/=16 on the Y-BOCS (defined as possible OCD). In surveys 2 and 3, 3.6% (305/8162) and 3.5% (305/8511) of participants had scores indicative of possible OCD, respectively. The Y-BOCS score, anxiety level, quarantine level, and intensity of fear were significantly lower at surveys 2 and 3 than at survey 1 (P<.001 for all). Compared to those with a lower Y-BOCS score (<16), participants with possible OCD expressed greater intensity of fear and had higher SAS standard scores (P<.001). The regression linear analysis indicated that intensity of fear was positively correlated to the rate of possible OCD and the average total scores for the Y-BOCS in each survey (P<.001 for all). Multiple regressions showed that those with a higher intensity of fear, a higher anxiety level, of male gender, with sibling(s), and majoring in a nonmedicine discipline had a greater chance of having a higher Y-BOCS score in all surveys. These results were redemonstrated in the 5827 participants who completed both surveys 1 and 2 and in the 4006 participants who completed all three surveys. Furthermore, in matched participants, the Y-BOCS score was negatively correlated to changes in intensity of fear (r=0.74 for survey 2, P<.001; r=0.63 for survey 3, P=.006). CONCLUSIONS: Our findings indicate that fear of COVID-19 was associated with a greater Y-BOCS score, suggesting that an environment (COVID-19 pandemic) x psychology (fear and/or anxiety) interaction might be involved in OCD and that a fear of negative events might play a role in the etiology of OCD.
  • |*Health Surveys[MESH]
  • |*Universities[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Anxiety/epidemiology/psychology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology/*psychology[MESH]
  • |Fear[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Obsessive-Compulsive Disorder/*epidemiology/psychology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/*psychology[MESH]
  • |Prospective Studies[MESH]
  • |Psychiatric Status Rating Scales[MESH]
  • |Students/*psychology/*statistics & numerical data[MESH]


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