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10.3390/nu12092757 http://scihub22266oqcxt.onion/10.3390/nu12092757 32927735!7551780!32927735     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nutrients 2020 ; 12 (9): ä Nephropedia Template TP {{tp|p=32927735|t=2020. Vitamin D Deficiency and Outcome of COVID-19 Patients |pdf=|usr=}}{{32927735}} gab.com Text Vitamin D Deficiency and Outcome of COVID-19 Patients JO: Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32927735 #FOAvip Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses an enormous challenge to health care systems throughout the world. Without causal treatment, identification of modifiable prognostic factors may help to improve outcomes. To explore possible associations of vitamin D (VitD) status with disease severity and survival, we studied 185 patients diagnosed with coronavirus disease 2019 (COVID-19) and treated at our center. VitD status at first presentation was assessed retrospectively using accredited laboratory methods. VitD deficiency was defined as serum total 25-hydroxyvitamin D level < 12 ng/mL (<30 nM). Primary endpoint was severe course of disease (i.e., need for invasive mechanical ventilation and/or death, IMV/D). Within a median observation period of 66 days (range 2-92), 23 patients required IMV. A total of 28 patients had IMV/D, including 16 deaths. Ninety-three (50%) patients required hospitalization (inpatient subgroup). A total of 41 (22%) patients were VitD deficient. When adjusted for age, gender, and comorbidities, VitD deficiency was associated with higher risk of IMV/D and death (HR 6.12, 95% CI 2.79-13.42, p < 0.001 and HR 14.73, 95% CI 4.16-52.19, p < 0.001, respectively). Similar correlations were observed in the inpatient subgroup. Our study demonstrates an association between VitD deficiency and severity/mortality of COVID-19, highlighting the need for interventional studies on VitD supplementation in SARS-CoV-2 infected individuals. Twit Text FOAVip Vitamin D Deficiency and Outcome of COVID-19 Patients ????Nutrients http://www.kidney.de/pget.php?&tw=1&pmid=32927735 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32927735 #FOAvip English Wikipedia <ref>{{Cite pmid|32927735}}</ref> Vitamin D Deficiency and Outcome of COVID-19 Patients #MMPMID32927735 Radujkovic A; Hippchen T; Tiwari-Heckler S; Dreher S; Boxberger M; Merle U Nutrients 2020[Sep]; 12 (9): ä PMID32927735show ga Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses an enormous challenge to health care systems throughout the world. Without causal treatment, identification of modifiable prognostic factors may help to improve outcomes. To explore possible associations of vitamin D (VitD) status with disease severity and survival, we studied 185 patients diagnosed with coronavirus disease 2019 (COVID-19) and treated at our center. VitD status at first presentation was assessed retrospectively using accredited laboratory methods. VitD deficiency was defined as serum total 25-hydroxyvitamin D level < 12 ng/mL (<30 nM). Primary endpoint was severe course of disease (i.e., need for invasive mechanical ventilation and/or death, IMV/D). Within a median observation period of 66 days (range 2-92), 23 patients required IMV. A total of 28 patients had IMV/D, including 16 deaths. Ninety-three (50%) patients required hospitalization (inpatient subgroup). A total of 41 (22%) patients were VitD deficient. When adjusted for age, gender, and comorbidities, VitD deficiency was associated with higher risk of IMV/D and death (HR 6.12, 95% CI 2.79-13.42, p < 0.001 and HR 14.73, 95% CI 4.16-52.19, p < 0.001, respectively). Similar correlations were observed in the inpatient subgroup. Our study demonstrates an association between VitD deficiency and severity/mortality of COVID-19, highlighting the need for interventional studies on VitD supplementation in SARS-CoV-2 infected individuals. |*Betacoronavirus[MESH] |Aged[MESH] |COVID-19[MESH] |Coronavirus Infections/blood/*mortality/virology[MESH] |Female[MESH] |Germany/epidemiology[MESH] |Hospitalization/statistics & numerical data[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH] |Nutritional Status[MESH] |Pandemics[MESH] |Pneumonia, Viral/blood/*mortality/virology[MESH] |Prognosis[MESH] |Prospective Studies[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Vitamin D Deficiency/blood/*mortality/virology[MESH]Vitamin D Deficiency and Outcome of COVID-19 Patients (epmc).pdf DeepDyve Pubget Overpricing