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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Diabetes+Res+Clin+Pract 2020 ; 169 (ä): 108440 Nephropedia Template TP
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Glycemic control in people with type 1 diabetes using a hybrid closed loop system and followed by telemedicine during the COVID-19 pandemic in Italy #MMPMID32926958
Longo M; Caruso P; Petrizzo M; Castaldo F; Sarnataro A; Gicchino M; Bellastella G; Esposito K; Maiorino MI
Diabetes Res Clin Pract 2020[Nov]; 169 (ä): 108440 PMID32926958show ga
AIMS: This study aims at evaluating the metrics of glycemic control in people with type 1 diabetes using the hybrid closed loop (HCL) system during the COVID-19 lockdown. METHODS: This is a retrospective study of thirty adults with type 1 diabetes using HCL and followed with telemedicine at an Italian University Hospital. Data on metrics of glucose control were collected at different times: two weeks before the lockdown (Time 0), first two weeks of lockdown (Time 1), last two weeks of lockdown (Time 2) and first two weeks after the lockdown (Time 3). The primary endpoint was the change in glucose management indicator (GMI) across the different time points. RESULTS: GMI did not worsen over time (Time 1 vs Time 3, 7% vs 6.9%, P < 0.05), whereas a reduction of mean glucose (P = 0.004) and indices of glucose variability was observed. Time in range (TIR) significantly increased (68.5% vs 73.5%, P = 0.012), and time above range (TAR) level 2 (251-400 mg/dL) significantly decreased (P = 0.002). The improvement of TIR and glucose variability was mainly observed in participants < 35 years. CONCLUSIONS: Adults with type 1 diabetes using HCL showed a significant improvement of most of the metrics of glucose control during the COVID-19 lockdown.
|*Glycemic Control[MESH]
|Adult[MESH]
|Blood Glucose Self-Monitoring[MESH]
|Blood Glucose/*analysis[MESH]
|COVID-19/*complications/virology[MESH]
|Diabetes Mellitus, Type 1/blood/*drug therapy/epidemiology/virology[MESH]