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10.1080/17425247.2021.1823964 http://scihub22266oqcxt.onion/10.1080/17425247.2021.1823964 32924651!9355143!32924651     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Opin+Drug+Deliv 2021 ; 18 (2): 151-167 Nephropedia Template TP {{tp|p=32924651|t=2021. Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases |pdf=|usr=}}{{32924651}} gab.com Text Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases JO: Expert Opin Drug Deliv http://www.kidney.de/pget.php?&tw=1&pmid=32924651 #FOAvip INTRODUCTION: Infectious pathogens are global disrupters. Progress in biomedical science and technology has expanded the public health arsenal against infectious diseases. Specifically, vaccination has reduced the burden of infectious pathogens. Engineering systemic immunity by harnessing the cutaneous immune network has been particularly attractive since the skin is an easily accessible immune-responsive organ. Recent advances in skin-targeted drug delivery strategies have enabled safe, patient-friendly, and controlled deployment of vaccines to cutaneous microenvironments for inducing long-lived pathogen-specific immunity to mitigate infectious diseases, including COVID-19. AREAS COVERED: This review briefly discusses the basics of cutaneous immunomodulation and provides a concise overview of emerging skin-targeted drug delivery systems that enable safe, minimally invasive, and effective intracutaneous administration of vaccines for engineering systemic immune responses to combat infectious diseases. EXPERT OPINION: In-situ engineering of the cutaneous microenvironment using emerging skin-targeted vaccine delivery systems offers remarkable potential to develop diverse immunization strategies against pathogens. Mechanistic studies with standard correlates of vaccine efficacy will be important to compare innovative intracutaneous drug delivery strategies to each other and to existing clinical approaches. Cost-benefit analyses will be necessary for developing effective commercialization strategies. Significant involvement of industry and/or government will be imperative for successfully bringing novel skin-targeted vaccine delivery methods to market for their widespread use. Twit Text FOAVip Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases ????Expert Opin Drug Deliv http://www.kidney.de/pget.php?&tw=1&pmid=32924651 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32924651 #FOAvip English Wikipedia <ref>{{Cite pmid|32924651}}</ref> Emerging skin-targeted drug delivery strategies to engineer immunity: A focus on infectious diseases #MMPMID32924651 Korkmaz E; Balmert SC; Carey CD; Erdos G; Falo LD Jr Expert Opin Drug Deliv 2021[Feb]; 18 (2): 151-167 PMID32924651show ga INTRODUCTION: Infectious pathogens are global disrupters. Progress in biomedical science and technology has expanded the public health arsenal against infectious diseases. Specifically, vaccination has reduced the burden of infectious pathogens. Engineering systemic immunity by harnessing the cutaneous immune network has been particularly attractive since the skin is an easily accessible immune-responsive organ. Recent advances in skin-targeted drug delivery strategies have enabled safe, patient-friendly, and controlled deployment of vaccines to cutaneous microenvironments for inducing long-lived pathogen-specific immunity to mitigate infectious diseases, including COVID-19. AREAS COVERED: This review briefly discusses the basics of cutaneous immunomodulation and provides a concise overview of emerging skin-targeted drug delivery systems that enable safe, minimally invasive, and effective intracutaneous administration of vaccines for engineering systemic immune responses to combat infectious diseases. EXPERT OPINION: In-situ engineering of the cutaneous microenvironment using emerging skin-targeted vaccine delivery systems offers remarkable potential to develop diverse immunization strategies against pathogens. Mechanistic studies with standard correlates of vaccine efficacy will be important to compare innovative intracutaneous drug delivery strategies to each other and to existing clinical approaches. Cost-benefit analyses will be necessary for developing effective commercialization strategies. Significant involvement of industry and/or government will be imperative for successfully bringing novel skin-targeted vaccine delivery methods to market for their widespread use. |Adjuvants, Immunologic/administration & dosage[MESH] |Administration, Cutaneous[MESH] |Animals[MESH] |Antigens/administration & dosage[MESH] |Biocompatible Materials/administration & dosage/chemistry[MESH] |COVID-19 Vaccines/administration & dosage[MESH] |COVID-19/prevention & control[MESH] |Cellular Microenvironment/immunology[MESH] |Communicable Disease Control/*methods[MESH] |Drug Delivery Systems/*methods[MESH] |Humans[MESH] |Nanoparticles/administration & dosage/chemistry[MESH] |SARS-CoV-2[MESH] |Skin/*immunology/metabolism[MESH] |Vaccination/*methods[MESH]Emerging skin-targeted drug delivery strategies to engineer immunity: (epmc).pdf DeepDyve Pubget Overpricing