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suck abstract from ncbi


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pmid32924345      J+Korean+Med+Sci 2020 ; ä (ä): ä
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  • Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 Stability in Multiple Water Matrices #MMPMID32924345
  • Lee YJ; Kim JH; Choi BS; Choi JH; Jeong YI
  • J Korean Med Sci 2020[Sep]; ä (ä): ä PMID32924345show ga
  • The advent of the global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates a thorough study of the stability and transmissibility in the environment. We characterized the stability of SARS-CoV-2 in three water matrices: fresh, tap, and seawater. The minimum infective dose of SARS-CoV-2 in Vero cells was confirmed to be 10(3) PFU/mL. The stability of SARS-CoV-2 varied according to the water matrix: infective SARS-CoV-2 was undetectable after treatment with fresh water and seawater, but remained detectable for 2 days in tap water, when starting with an initial concentration of 10(4) PFU/mL. When the starting concentration was increased to 10(5) PFU/mL, a similar trend was observed. In addition, viral RNA persisted longer than infectious virus in all water matrices. This study was conducted in stagnant water containing a significantly high titer of virus, thus, human-to-human transmission of SARS-CoV-2 through the actual aquatic environment is expected to be rare.
  • |*Water Microbiology[MESH]
  • |*Water Supply[MESH]
  • |Animals[MESH]
  • |Betacoronavirus/*isolation & purification/physiology[MESH]
  • |COVID-19[MESH]
  • |Chlorocebus aethiops[MESH]
  • |Coronavirus Infections/transmission/*virology[MESH]
  • |Drinking Water/*virology[MESH]
  • |Fresh Water/*virology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/transmission/*virology[MESH]
  • |SARS-CoV-2[MESH]
  • |Seawater/*virology[MESH]
  • |Vero Cells[MESH]
  • |Viral Load[MESH]
  • |Virus Cultivation[MESH]


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