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10.1080/2162402X.2020.1789284 http://scihub22266oqcxt.onion/10.1080/2162402X.2020.1789284 32923151!7458592!32923151     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncoimmunology 2020 ; 9 (1): 1789284 Nephropedia Template TP {{tp|p=32923151|t=2020. Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses |pdf=|usr=}}{{32923151}} gab.com Text Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses JO: Oncoimmunology http://www.kidney.de/pget.php?&tw=1&pmid=32923151 #FOAvip Amid controversial reports that COVID-19 can be treated with a combination of the antimalarial drug hydroxychloroquine (HCQ) and the antibiotic azithromycin (AZI), a clinical trial (ONCOCOVID, NCT04341207) was launched at Gustave Roussy Cancer Campus to investigate the utility of this combination therapy in cancer patients. In this preclinical study, we investigated whether the combination of HCQ+AZI would be compatible with the therapeutic induction of anticancer immune responses. For this, we used doses of HCQ and AZI that affect whole-body physiology (as indicated by a partial blockade in cardiac and hepatic autophagic flux for HCQ and a reduction in body weight for AZI), showing that their combined administration did not interfere with tumor growth control induced by the immunogenic cell death inducer oxaliplatin. Moreover, the HCQ+AZI combination did not affect the capacity of a curative regimen (cisplatin + crizotinib + PD-1 blockade) to eradicate established orthotopic lung cancers in mice. In conclusion, it appears that HCQ+AZI does not interfere with the therapeutic induction of therapeutic anticancer immune responses. Twit Text FOAVip Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses ????Oncoimmunology http://www.kidney.de/pget.php?&tw=1&pmid=32923151 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32923151 #FOAvip English Wikipedia <ref>{{Cite pmid|32923151}}</ref> Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses #MMPMID32923151 Liu P; Zhao L; Ferrere G; Alves-Costa-Silva C; Ly P; Wu Q; Tian AL; Derosa L; Zitvogel L; Kepp O; Kroemer G Oncoimmunology 2020[Jul]; 9 (1): 1789284 PMID32923151show ga Amid controversial reports that COVID-19 can be treated with a combination of the antimalarial drug hydroxychloroquine (HCQ) and the antibiotic azithromycin (AZI), a clinical trial (ONCOCOVID, NCT04341207) was launched at Gustave Roussy Cancer Campus to investigate the utility of this combination therapy in cancer patients. In this preclinical study, we investigated whether the combination of HCQ+AZI would be compatible with the therapeutic induction of anticancer immune responses. For this, we used doses of HCQ and AZI that affect whole-body physiology (as indicated by a partial blockade in cardiac and hepatic autophagic flux for HCQ and a reduction in body weight for AZI), showing that their combined administration did not interfere with tumor growth control induced by the immunogenic cell death inducer oxaliplatin. Moreover, the HCQ+AZI combination did not affect the capacity of a curative regimen (cisplatin + crizotinib + PD-1 blockade) to eradicate established orthotopic lung cancers in mice. In conclusion, it appears that HCQ+AZI does not interfere with the therapeutic induction of therapeutic anticancer immune responses. |*COVID-19 Drug Treatment[MESH] |Animals[MESH] |Antineoplastic Combined Chemotherapy Protocols/*administration & dosage/pharmacokinetics[MESH] |Azithromycin/*administration & dosage/pharmacokinetics[MESH] |COVID-19/immunology/virology[MESH] |Cell Line, Tumor[MESH] |Cisplatin/administration & dosage/pharmacokinetics[MESH] |Clinical Trials, Phase II as Topic[MESH] |Crizotinib/administration & dosage/pharmacokinetics[MESH] |Disease Models, Animal[MESH] |Drug Evaluation, Preclinical[MESH] |Drug Interactions[MESH] |Drug Therapy, Combination/methods[MESH] |Female[MESH] |France[MESH] |Humans[MESH] |Hydroxychloroquine/*administration & dosage/pharmacokinetics[MESH] |Mice[MESH] |Neoplasms/*drug therapy/immunology[MESH] |Oxaliplatin/administration & dosage/pharmacokinetics[MESH] |Programmed Cell Death 1 Receptor/antagonists & inhibitors/immunology[MESH]Combination treatments with hydroxychloroquine and azithromycin are co(epmc).pdf DeepDyve Pubget Overpricing