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10.7150/ijms.48074

http://scihub22266oqcxt.onion/10.7150/ijms.48074
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32922173!7484669!32922173
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suck abstract from ncbi


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pmid32922173      Int+J+Med+Sci 2020 ; 17 (14): 2125-2132
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  • Fangcang Shelter Hospital in Wuhan: A radiographic report on a cohort of 98 COVID-19 patients #MMPMID32922173
  • Guo T; Liu X; Xu C; Wang J; Yang L; Shi H; Dai M
  • Int J Med Sci 2020[]; 17 (14): 2125-2132 PMID32922173show ga
  • Objectives: To present the temporal changes of CT manifestations in COVID-19 patients from a single fangcang shelter hospital and to facilitate the understanding of the disease course. Materials and Methods: This retrospective study included 98 patients (males: females, 43:55, mean year, 49+/-12 years) with confirmed COVID-19 at Jianghan fangcang shelter hospital admitted between Feb 05, 2020, and Feb 09, 2020, who had initial chest CTs at our hospital. Radiographic features and CT scores were analyzed. Results: A total of 267 CT scans of 98 patients were evaluated. Our study showed a high median total CT score of 7 within the first week from symptom onset, peaked in the 2(nd) week at 10, followed by persistently high levels of CT score with 9.5, 7 and 7 for the week 3, 4, and >4, respectively, and a prolonged median disease course (30 days, the median interval between the onset of initial symptoms and discharge). Ground-glass opacity (GGO) (58%, 41/71) was the earliest and most frequent finding in week 1. Consolidation (26%, 14/53) and mixed pattern (40%, 21/53) were predominant patterns in 2(nd) week. GGO and reticular were the main patterns of later phase CT scans in patients with relatively advanced diseases who had longer illness duration (>/=4 weeks). Among the 94 CT abnormalities obtained within 3 days from the twice RT-PCR test turned negative, the mixed pattern was mainly presented in patients with disease duration of 2-3 weeks, for GGO and reticular were common during the whole course. Conclusion: Discharged patients from fangcang shelter hospital demonstrated a high extent of lung abnormalities on CT within the first week from symptom onset, peaked at 2(nd) week, followed by persistence of high levels and a prolonged median disease course. GGO was the predominant pattern in week 1, consolidation and mixed pattern in 2(nd) week, whereas GGO and reticular patterns in later stages (>/=4 weeks).
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/genetics/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |China/epidemiology[MESH]
  • |Clinical Laboratory Techniques/methods/*statistics & numerical data[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology/virology[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lung/*diagnostic imaging[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Mobile Health Units[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*diagnosis/epidemiology/virology[MESH]
  • |RNA, Viral/isolation & purification[MESH]
  • |Retrospective Studies[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Tomography, X-Ray Computed/*statistics & numerical data[MESH]


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