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10.1016/j.ijid.2020.09.014 http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.09.014 32920234!7482607!32920234     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Infect+Dis 2020 ; 100 (ä): 343-349 Nephropedia Template TP {{tp|p=32920234|t=2020. COVID-19: Poor outcomes in patients with zinc deficiency |pdf=|usr=}}{{32920234}} gab.com Text COVID-19: Poor outcomes in patients with zinc deficiency JO: Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32920234 #FOAvip BACKGROUND: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19). However, we do not know the clinical significance of serum Zinc levels in COVID-19 patients. The aim of this study was to determine the clinical significance of serum zinc in COVID-19 patients and to establish a correlation with disease severity. METHODS: This was a prospective study of fasting zinc levels in COVID-19 patients at the time of hospitalization. An initial comparative analysis was conducted between COVID-19 patients and healthy controls. COVID-19 patients with zinc deficiency were compared to those with normal zinc levels. RESULTS: COVID-19 patients (n = 47) showed significantly lower zinc levels when compared to healthy controls (n = 45): median 74.5 (interquartile range 53.4-94.6) mug/dl vs 105.8 (interquartile range 95.65-120.90) mug/dl (p < 0.001). Amongst the COVID-19 patients, 27 (57.4%) were found to be zinc deficient. These patients were found to have higher rates of complications (p = 0.009), acute respiratory distress syndrome (18.5% vs 0%, p = 0.06), corticosteroid therapy (p = 0.02), prolonged hospital stay (p = 0.05), and increased mortality (18.5% vs 0%, p = 0.06). The odds ratio (OR) of developing complications was 5.54 for zinc deficient COVID-19 patients. CONCLUSIONS: The study data clearly show that a significant number of COVID-19 patients were zinc deficient. These zinc deficient patients developed more complications, and the deficiency was associated with a prolonged hospital stay and increased mortality. Twit Text FOAVip COVID-19: Poor outcomes in patients with zinc deficiency ????Int J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32920234 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32920234 #FOAvip English Wikipedia <ref>{{Cite pmid|32920234}}</ref> COVID-19: Poor outcomes in patients with zinc deficiency #MMPMID32920234 Jothimani D; Kailasam E; Danielraj S; Nallathambi B; Ramachandran H; Sekar P; Manoharan S; Ramani V; Narasimhan G; Kaliamoorthy I; Rela M Int J Infect Dis 2020[Nov]; 100 (ä): 343-349 PMID32920234show ga BACKGROUND: Zinc is a trace element with potent immunoregulatory and antiviral properties, and is utilized in the treatment of coronavirus disease 2019 (COVID-19). However, we do not know the clinical significance of serum Zinc levels in COVID-19 patients. The aim of this study was to determine the clinical significance of serum zinc in COVID-19 patients and to establish a correlation with disease severity. METHODS: This was a prospective study of fasting zinc levels in COVID-19 patients at the time of hospitalization. An initial comparative analysis was conducted between COVID-19 patients and healthy controls. COVID-19 patients with zinc deficiency were compared to those with normal zinc levels. RESULTS: COVID-19 patients (n = 47) showed significantly lower zinc levels when compared to healthy controls (n = 45): median 74.5 (interquartile range 53.4-94.6) mug/dl vs 105.8 (interquartile range 95.65-120.90) mug/dl (p < 0.001). Amongst the COVID-19 patients, 27 (57.4%) were found to be zinc deficient. These patients were found to have higher rates of complications (p = 0.009), acute respiratory distress syndrome (18.5% vs 0%, p = 0.06), corticosteroid therapy (p = 0.02), prolonged hospital stay (p = 0.05), and increased mortality (18.5% vs 0%, p = 0.06). The odds ratio (OR) of developing complications was 5.54 for zinc deficient COVID-19 patients. CONCLUSIONS: The study data clearly show that a significant number of COVID-19 patients were zinc deficient. These zinc deficient patients developed more complications, and the deficiency was associated with a prolonged hospital stay and increased mortality. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19/blood/*complications/therapy[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Length of Stay[MESH] |Male[MESH] |Middle Aged[MESH] |Odds Ratio[MESH] |Pandemics[MESH] |Prospective Studies[MESH] |SARS-CoV-2[MESH] |Treatment Outcome[MESH] |Young Adult[MESH]COVID-19: Poor outcomes in patients with zinc deficiency (epmc).pdf DeepDyve Pubget Overpricing