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10.1038/s41579-020-00441-3 http://scihub22266oqcxt.onion/10.1038/s41579-020-00441-3 32913297!7481764!32913297     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Microbiol 2020 ; 18 (12): 690-704 Nephropedia Template TP {{tp|p=32913297|t=2020. Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa |pdf=|usr=}}{{32913297}} gab.com Text Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa JO: Nat Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32913297 #FOAvip The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many developed countries have implemented widespread testing and have rapidly mobilized research programmes to develop vaccines and therapeutics. However, these approaches may be impractical in Africa, where the infrastructure for testing is poorly developed and owing to the limited manufacturing capacity to produce pharmaceuticals. Furthermore, a large burden of HIV-1 and tuberculosis in Africa could exacerbate the severity of infection and may affect vaccine immunogenicity. This Review discusses global efforts to develop diagnostics, therapeutics and vaccines, with these considerations in mind. We also highlight vaccine and diagnostic production platforms that are being developed in Africa and that could be translated into clinical development through appropriate partnerships for manufacture. Twit Text FOAVip Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa ????Nat Rev Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32913297 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32913297 #FOAvip English Wikipedia <ref>{{Cite pmid|32913297}}</ref> Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa #MMPMID32913297 Margolin E; Burgers WA; Sturrock ED; Mendelson M; Chapman R; Douglass N; Williamson AL; Rybicki EP Nat Rev Microbiol 2020[Dec]; 18 (12): 690-704 PMID32913297show ga The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a global pandemic, prompting unprecedented efforts to contain the virus. Many developed countries have implemented widespread testing and have rapidly mobilized research programmes to develop vaccines and therapeutics. However, these approaches may be impractical in Africa, where the infrastructure for testing is poorly developed and owing to the limited manufacturing capacity to produce pharmaceuticals. Furthermore, a large burden of HIV-1 and tuberculosis in Africa could exacerbate the severity of infection and may affect vaccine immunogenicity. This Review discusses global efforts to develop diagnostics, therapeutics and vaccines, with these considerations in mind. We also highlight vaccine and diagnostic production platforms that are being developed in Africa and that could be translated into clinical development through appropriate partnerships for manufacture. |*SARS-CoV-2/physiology[MESH] |Africa/epidemiology[MESH] |COVID-19/*diagnosis/epidemiology/*prevention & control/*therapy[MESH] |Clinical Decision-Making[MESH] |Coinfection[MESH] |Disease Management[MESH] |Disease Susceptibility[MESH] |Humans[MESH] |Population Surveillance[MESH] |Vaccination[MESH] |Vaccinology/methods[MESH]Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Afr(epmc).pdf DeepDyve Pubget Overpricing