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10.3390/ijms21186559 http://scihub22266oqcxt.onion/10.3390/ijms21186559 32911736!7555889!32911736     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2020 ; 21 (18): ä Nephropedia Template TP {{tp|p=32911736|t=2020. Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Permeability Transition Pore |pdf=|usr=}}{{32911736}} gab.com Text Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Permeability Transition Pore JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32911736 #FOAvip Diabetes mellitus is one of the most common metabolic diseases in the developed world, and is associated either with the impaired secretion of insulin or with the resistance of cells to the actions of this hormone (type I and type II diabetes, respectively). In both cases, a common pathological change is an increase in blood glucose-hyperglycemia, which eventually can lead to serious damage to the organs and tissues of the organism. Mitochondria are one of the main targets of diabetes at the intracellular level. This review is dedicated to the analysis of recent data regarding the role of mitochondrial dysfunction in the development of diabetes mellitus. Specific areas of focus include the involvement of mitochondrial calcium transport systems and a pathophysiological phenomenon called the permeability transition pore in the pathogenesis of diabetes mellitus. The important contribution of these systems and their potential relevance as therapeutic targets in the pathology are discussed. Twit Text FOAVip Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Permeability Transition Pore ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32911736 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32911736 #FOAvip English Wikipedia <ref>{{Cite pmid|32911736}}</ref> Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Permeability Transition Pore #MMPMID32911736 Belosludtsev KN; Belosludtseva NV; Dubinin MV Int J Mol Sci 2020[Sep]; 21 (18): ä PMID32911736show ga Diabetes mellitus is one of the most common metabolic diseases in the developed world, and is associated either with the impaired secretion of insulin or with the resistance of cells to the actions of this hormone (type I and type II diabetes, respectively). In both cases, a common pathological change is an increase in blood glucose-hyperglycemia, which eventually can lead to serious damage to the organs and tissues of the organism. Mitochondria are one of the main targets of diabetes at the intracellular level. This review is dedicated to the analysis of recent data regarding the role of mitochondrial dysfunction in the development of diabetes mellitus. Specific areas of focus include the involvement of mitochondrial calcium transport systems and a pathophysiological phenomenon called the permeability transition pore in the pathogenesis of diabetes mellitus. The important contribution of these systems and their potential relevance as therapeutic targets in the pathology are discussed. |Animals[MESH] |Blood Glucose/metabolism[MESH] |Calcium/metabolism[MESH] |Diabetes Mellitus, Type 2/*metabolism[MESH] |Glucose/metabolism[MESH] |Humans[MESH] |Hyperglycemia/metabolism[MESH] |Insulin Resistance/physiology[MESH] |Insulin/metabolism[MESH] |Mitochondria/*metabolism[MESH] |Mitochondrial Diseases/metabolism/*physiopathology[MESH] |Mitochondrial Dynamics/physiology[MESH] |Mitochondrial Membrane Transport Proteins/metabolism[MESH]Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Perm(epmc).pdf DeepDyve Pubget Overpricing