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10.1016/j.nut.2020.110948

http://scihub22266oqcxt.onion/10.1016/j.nut.2020.110948
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32911430!7381407!32911430
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suck abstract from ncbi


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pmid32911430      Nutrition 2020 ; 79-80 (ä): 110948
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  • Vitamin C as prophylaxis and adjunctive medical treatment for COVID-19? #MMPMID32911430
  • Feyaerts AF; Luyten W
  • Nutrition 2020[Nov]; 79-80 (ä): 110948 PMID32911430show ga
  • Severe acute respiratory syndrome coronavirus 2 causes the potentially fatal coronavirus disease 2019 (COVID-19). Already during the outbreak of the severe acute respiratory syndrome coronavirus 1, the use of vitamin C was suggested. Many patients with severe COVID-19 have elevated levels of the mediators interleukin-6 and endothelin-1. These mediators may explain the age dependence of COVID-19 pneumonia, the preponderance of male and obese or hypertensive patients, as well as of persons of color and smokers. There is clear evidence that vitamin C in high doses can reduce these mediators. Vitamin C is cheap and safe. Hence, using a relatively low dose of vitamin C as prophylaxis, and in cases of severe COVID-19, an (intravenous) high-dose regimen may be beneficial. Ongoing clinical trials are expected to provide more definitive evidence.
  • |*COVID-19 Drug Treatment[MESH]
  • |Animals[MESH]
  • |Ascorbic Acid/pharmacology/*therapeutic use[MESH]
  • |COVID-19/*prevention & control[MESH]
  • |Coronavirus[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Interleukin-6/metabolism[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]


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