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10.1016/j.placenta.2020.08.018 http://scihub22266oqcxt.onion/10.1016/j.placenta.2020.08.018 32911234!7443324!32911234     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Placenta 2020 ; 101 (ä): 13-29 Nephropedia Template TP {{tp|p=32911234|t=2020. A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection |pdf=|usr=}}{{32911234}} gab.com Text A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection JO: Placenta http://www.kidney.de/pget.php?&tw=1&pmid=32911234 #FOAvip The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, was first identified after a cluster of cases in Wuhan, China in December 2019. Whether vertical transmission or placental pathology might occur following maternal infection during pregnancy remains unknown. This review aimed to summarise all studies that examined the placenta or neonates following infection with SARS-CoV-2, or closely related highly pathogenic coronavirus (SARS-CoV-1, or the Middle East respiratory syndrome coronavirus (MERS-CoV)). Structured literature searches found 50 studies that met the inclusion criteria. Twenty studies reported placental histopathology findings in third trimester placentas following maternal SARS-CoV-2 infection. Using the Amsterdam Consensus criteria to categorise the histopathology results, evidence of both fetal vascular malperfusion (35.3% of cases; 95% Confidence Interval (CI) 27.7-43.0%) and maternal vascular malperfusion (46% of cases; 95% CI 38.0-54.0%) were reported, along with evidence of inflammation in the placentas (villitis 8.7% cases, intervillositis 5.3% of cases, chorioamnionitis 6% of cases). The placental pathologies observed in SARS-CoV-2 were consistent with findings following maternal SARS-CoV-1 infection. Of those tested, a minority of neonates (2%) and placental samples tested positive for SARS-CoV-2 infection (21%). Limited conclusions can be drawn about the effect of maternal SARS-CoV-2 infection on placental pathology as most lack control groups and the majority of reports followed third trimester infection. Collaboration to maximise the number of samples examined will increase the reliability and generalisability of findings. A better understanding of the association between maternal SARS-CoV-2 infection and placental pathology will inform maternity care during the coronavirus pandemic. Twit Text FOAVip A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection ????Placenta http://www.kidney.de/pget.php?&tw=1&pmid=32911234 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32911234 #FOAvip English Wikipedia <ref>{{Cite pmid|32911234}}</ref> A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection #MMPMID32911234 Sharps MC; Hayes DJL; Lee S; Zou Z; Brady CA; Almoghrabi Y; Kerby A; Tamber KK; Jones CJ; Adams Waldorf KM; Heazell AEP Placenta 2020[Nov]; 101 (ä): 13-29 PMID32911234show ga The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, was first identified after a cluster of cases in Wuhan, China in December 2019. Whether vertical transmission or placental pathology might occur following maternal infection during pregnancy remains unknown. This review aimed to summarise all studies that examined the placenta or neonates following infection with SARS-CoV-2, or closely related highly pathogenic coronavirus (SARS-CoV-1, or the Middle East respiratory syndrome coronavirus (MERS-CoV)). Structured literature searches found 50 studies that met the inclusion criteria. Twenty studies reported placental histopathology findings in third trimester placentas following maternal SARS-CoV-2 infection. Using the Amsterdam Consensus criteria to categorise the histopathology results, evidence of both fetal vascular malperfusion (35.3% of cases; 95% Confidence Interval (CI) 27.7-43.0%) and maternal vascular malperfusion (46% of cases; 95% CI 38.0-54.0%) were reported, along with evidence of inflammation in the placentas (villitis 8.7% cases, intervillositis 5.3% of cases, chorioamnionitis 6% of cases). The placental pathologies observed in SARS-CoV-2 were consistent with findings following maternal SARS-CoV-1 infection. Of those tested, a minority of neonates (2%) and placental samples tested positive for SARS-CoV-2 infection (21%). Limited conclusions can be drawn about the effect of maternal SARS-CoV-2 infection on placental pathology as most lack control groups and the majority of reports followed third trimester infection. Collaboration to maximise the number of samples examined will increase the reliability and generalisability of findings. A better understanding of the association between maternal SARS-CoV-2 infection and placental pathology will inform maternity care during the coronavirus pandemic. |*Infectious Disease Transmission, Vertical[MESH] |Betacoronavirus/*pathogenicity/physiology[MESH] |COVID-19[MESH] |Coronavirus Infections/epidemiology/*pathology/physiopathology/transmission[MESH] |Female[MESH] |Humans[MESH] |Infant, Newborn[MESH] |Pandemics[MESH] |Placenta/blood supply/*pathology/virology[MESH] |Placental Circulation/physiology[MESH] |Pneumonia, Viral/epidemiology/*pathology/physiopathology/transmission[MESH] |Pregnancy[MESH] |Pregnancy Complications, Infectious/epidemiology/*pathology/physiopathology/virology[MESH] |SARS-CoV-2[MESH]A structured review of placental morphology and histopathological lesi(epmc).pdf DeepDyve Pubget Overpricing