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10.1016/j.pharmthera.2020.107672 http://scihub22266oqcxt.onion/10.1016/j.pharmthera.2020.107672 32910933!7476892!32910933     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32910933&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pharmacol+Ther 2020 ; 216 (ä): 107672 Nephropedia Template TP {{tp|p=32910933|t=2020. Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 |pdf=|usr=}}{{32910933}} gab.com Text Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 JO: Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32910933 #FOAvip Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for the treatment and prevention of malaria, and the treatment of autoimmune diseases for several decades. As their new mechanisms of actions are identified in recent years, CQ and HCQ have wider therapeutic applications, one of which is to treat viral infectious diseases. Since the pandemic of the coronavirus disease 2019 (COVID-19), CQ and HCQ have been subjected to a number of in vitro and in vivo tests, and their therapeutic prospects for COVID-19 have been proposed. In this article, the applications and mechanisms of action of CQ and HCQ in their conventional fields of anti-malaria and anti-rheumatism, as well as their repurposing prospects in anti-virus are reviewed. The current trials and future potential of CQ and HCQ in combating COVID-19 are discussed. Twit Text FOAVip Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 ????Pharmacol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32910933 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32910933 #FOAvip English Wikipedia <ref>{{Cite pmid|32910933}}</ref> Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 #MMPMID32910933 Lei ZN; Wu ZX; Dong S; Yang DH; Zhang L; Ke Z; Zou C; Chen ZS Pharmacol Ther 2020[Dec]; 216 (ä): 107672 PMID32910933show ga Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for the treatment and prevention of malaria, and the treatment of autoimmune diseases for several decades. As their new mechanisms of actions are identified in recent years, CQ and HCQ have wider therapeutic applications, one of which is to treat viral infectious diseases. Since the pandemic of the coronavirus disease 2019 (COVID-19), CQ and HCQ have been subjected to a number of in vitro and in vivo tests, and their therapeutic prospects for COVID-19 have been proposed. In this article, the applications and mechanisms of action of CQ and HCQ in their conventional fields of anti-malaria and anti-rheumatism, as well as their repurposing prospects in anti-virus are reviewed. The current trials and future potential of CQ and HCQ in combating COVID-19 are discussed. |*Betacoronavirus[MESH] |Animals[MESH] |Antimalarials/pharmacokinetics/*therapeutic use[MESH] |Antirheumatic Agents/pharmacokinetics/*therapeutic use[MESH] |Antiviral Agents/pharmacokinetics/*therapeutic use[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Chloroquine/pharmacokinetics/*therapeutic use[MESH] |Coronavirus Infections/*drug therapy/metabolism[MESH] |Drug Repositioning[MESH] |Humans[MESH] |Malaria/drug therapy[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy/metabolism[MESH]Chloroquine and hydroxychloroquine in the treatment of malaria and rep(epmc).pdf DeepDyve Pubget Overpricing