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10.1155/2020/1352982 http://scihub22266oqcxt.onion/10.1155/2020/1352982 32908574!7463400!32908574     free     free     free       Comput+Math+Methods+Med 2020 ; 2020 (ä): 1352982 Nephropedia Template TP {{tp|p=32908574|t=2020. A Model for SARS-CoV-2 Infection with Treatment |pdf=|usr=}}{{32908574}} gab.com Text A Model for SARS-CoV-2 Infection with Treatment JO: Comput Math Methods Med http://www.kidney.de/pget.php?&tw=1&pmid=32908574 #FOAvip The current emergence of coronavirus (SARS-CoV-2) puts the world in threat. The structural research on the receptor recognition by SARS-CoV-2 has identified the key interactions between SARS-CoV-2 spike protein and its host (epithelial cell) receptor, also known as angiotensin-converting enzyme 2 (ACE2). It controls both the cross-species and human-to-human transmissions of SARS-CoV-2. In view of this, we propose and analyze a mathematical model for investigating the effect of CTL responses over the viral mutation to control the viral infection when a postinfection immunostimulant drug (pidotimod) is administered at regular intervals. Dynamics of the system with and without impulses have been analyzed using the basic reproduction number. This study shows that the proper dosing interval and drug dose both are important to eradicate the viral infection. Twit Text FOAVip A Model for SARS-CoV-2 Infection with Treatment ????Comput Math Methods Med http://www.kidney.de/pget.php?&tw=1&pmid=32908574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32908574 #FOAvip English Wikipedia <ref>{{Cite pmid|32908574}}</ref> A Model for SARS-CoV-2 Infection with Treatment #MMPMID32908574 Chatterjee AN; Al Basir F Comput Math Methods Med 2020[]; 2020 (ä): 1352982 PMID32908574show ga The current emergence of coronavirus (SARS-CoV-2) puts the world in threat. The structural research on the receptor recognition by SARS-CoV-2 has identified the key interactions between SARS-CoV-2 spike protein and its host (epithelial cell) receptor, also known as angiotensin-converting enzyme 2 (ACE2). It controls both the cross-species and human-to-human transmissions of SARS-CoV-2. In view of this, we propose and analyze a mathematical model for investigating the effect of CTL responses over the viral mutation to control the viral infection when a postinfection immunostimulant drug (pidotimod) is administered at regular intervals. Dynamics of the system with and without impulses have been analyzed using the basic reproduction number. This study shows that the proper dosing interval and drug dose both are important to eradicate the viral infection. |*Betacoronavirus/genetics/immunology[MESH] |*Models, Biological[MESH] |Adjuvants, Immunologic/*administration & dosage[MESH] |Angiotensin-Converting Enzyme 2[MESH] |Basic Reproduction Number[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Computer Simulation[MESH] |Coronavirus Infections/*drug therapy/epidemiology/immunology[MESH] |Dose-Response Relationship, Drug[MESH] |Host Microbial Interactions/drug effects/immunology[MESH] |Humans[MESH] |Mathematical Concepts[MESH] |Mutation[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/physiology[MESH] |Pneumonia, Viral/*drug therapy/epidemiology/immunology[MESH] |Pyrrolidonecarboxylic Acid/administration & dosage/*analogs & derivatives[MESH] |Receptors, Virus/physiology[MESH] |SARS-CoV-2[MESH] |Spike Glycoprotein, Coronavirus/genetics/immunology[MESH] |T-Lymphocytes, Cytotoxic/immunology[MESH]A Model for SARS-CoV-2 Infection with Treatment (epmc).pdf DeepDyve Pubget Overpricing