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Retrospective analysis of nosocomial COVID-19: a comparison between patients with hematological disorders and other diseases #MMPMID32908046
Uchida T; Takagi Y; Mizuno A; Okamura H; Saito H; Ide S; Ohara S; Inoue M; Hagihara M
Rinsho Ketsueki 2020[]; 61 (8): 857-864 PMID32908046show ga
Nosocomial coronavirus disease 2019 (COVID-19) had occurred at our hospital. We retrospectively analyzed the differences between patients with nosocomial COVID-19 and either hematological disease (n=40) or other diseases (n=57). The analysis was completed within 60 days for surviving patients. Among the patients with hematological disease and those with other diseases, there were 21 (52.5%) and 20 (35.1%) deaths, respectively. Although the patients with hematological disease received favipiravir more frequently than patients with other diseases (21 [52.5%] vs. 15 [35.3%], respectively; P<0.05), their median overall survival was poor (29 days; P=0.078). Furthermore, the median duration from oxygen therapy initiation to death or intubation was significantly shorter in the patients with hematological disease (5 days [range, 1-17 days] vs. 10 days [1-24 days], respectively; P<0.05). Furthermore, the patients with hematological disease and nosocomial COVID-19 exhibited more marked respiratory failure and poorer outcomes leading to death in a shorter time period than the patients with other diseases and nosocomial COVID-19.
Rinsho+Ketsueki 2020 ; 61 (8): 857-864
