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10.1017/S0007114520003529

http://scihub22266oqcxt.onion/10.1017/S0007114520003529
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32892755!7520638!32892755
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suck abstract from ncbi

pmid32892755      Br+J+Nutr 2021 ; 125 (6): 628-632
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  • Obesity, COVID-19 and innate immunometabolism #MMPMID32892755
  • Gleeson LE; Roche HM; Sheedy FJ
  • Br J Nutr 2021[Mar]; 125 (6): 628-632 PMID32892755show ga
  • As COVID-19 continues to spread worldwide, severe disease and mortality have been observed in obese patients. We discuss how obesity and obesity-associated factors such as 'meta-flammation', dietary fat intake and paradoxical suppression of the innate immune response within the pulmonary compartment may be crucial determinants in the host response to a novel viral pathogen. Modulation of immune cell bioenergetics and metabolic potential plays a central role in the innate immune response to infection, and as we strive to combat this new global health threat, immunometabolism of the innate immune system warrants attention.
  • |COVID-19/*immunology/mortality[MESH]
  • |Dietary Fats/immunology[MESH]
  • |Eating/immunology[MESH]
  • |Energy Metabolism/immunology[MESH]
  • |Humans[MESH]
  • |Immune System/*virology[MESH]
  • |Immunity, Innate/immunology[MESH]
  • |Inflammation[MESH]
  • |Obesity/*immunology/mortality/*virology[MESH]
  • |Respiratory System/immunology/virology[MESH]


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