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10.1111/ijcp.13698 http://scihub22266oqcxt.onion/10.1111/ijcp.13698 32892477!ä!32892477 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Clin+Pract 2021 ; 75 (4): e13698 Nephropedia Template TP {{tp|p=32892477|t=2021. Neutrophil/lymphocyte ratio-A marker of COVID-19 pneumonia severity |pdf=|usr=}}{{32892477}} gab.com Text Neutrophil/lymphocyte ratio-A marker of COVID-19 pneumonia severity JO: Int J Clin Pract http://www.kidney.de/pget.php?&tw=1&pmid=32892477 #FOAvip AIM: To determine the efficacy of neutrophil/lymphocyte ratio (NLR) as a marker of the severity of COVID-19 pneumonia in the South-Asian population. METHODS: This was a prospective, cross-sectional, analytic study conducted at HDU/ICU of District Headquarter Hospital, Faisalabad, Pakistan, from May through July 2020. Sixty-three eligible patients, admitted to the HDU/ICU, were prospectively enrolled in the study. Their NLR, C-reactive protein, serum albumin and serum fibrinogen were measured. Patients' demographic characteristics, comorbidities, clinical manifestations of COVID-19 infection, medication use and history of lung malignancy were retrieved from their medical history. Patients were categorised into either a general group (with mild COVID-19) or a heavy group (with moderate to severe COVID-19). RESULTS: There were significant differences between the two groups in diabetes prevalence, NLR, C-reactive protein and serum albumin. NLR and C-reactive protein were positively correlated (P < .001, P = .04, respectively) whereas serum albumin was negatively correlated (P = .009) with severe COVID-19. NLR was found to be an independent risk factor for severe COVID-19 pneumonia in the heavy group (OR = 1.264, 95% CI: 1.046~1.526, P = .015). The calculated AUC using ROC for NLR was 0.831, with an optimal limit of 4.795, sensitivity of 0.83 and specificity of 0.75, which is highly suggestive of NLR being a marker for the early detection of deteriorating severe COVID-19 infection. CONCLUSION: NLR can be used as an early warning signal for deteriorating severe COVID-19 infection and can provide an objective basis for early identification and management of severe COVID-19 pneumonia. Twit Text FOAVip Neutrophil/lymphocyte ratio-A marker of COVID-19 pneumonia severity ????Int J Clin Pract http://www.kidney.de/pget.php?&tw=1&pmid=32892477 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32892477 #FOAvip English Wikipedia <ref>{{Cite pmid|32892477}}</ref> Neutrophil/lymphocyte ratio-A marker of COVID-19 pneumonia severity #MMPMID32892477 Imran MM; Ahmad U; Usman U; Ali M; Shaukat A; Gul N Int J Clin Pract 2021[Apr]; 75 (4): e13698 PMID32892477show ga AIM: To determine the efficacy of neutrophil/lymphocyte ratio (NLR) as a marker of the severity of COVID-19 pneumonia in the South-Asian population. METHODS: This was a prospective, cross-sectional, analytic study conducted at HDU/ICU of District Headquarter Hospital, Faisalabad, Pakistan, from May through July 2020. Sixty-three eligible patients, admitted to the HDU/ICU, were prospectively enrolled in the study. Their NLR, C-reactive protein, serum albumin and serum fibrinogen were measured. Patients' demographic characteristics, comorbidities, clinical manifestations of COVID-19 infection, medication use and history of lung malignancy were retrieved from their medical history. Patients were categorised into either a general group (with mild COVID-19) or a heavy group (with moderate to severe COVID-19). RESULTS: There were significant differences between the two groups in diabetes prevalence, NLR, C-reactive protein and serum albumin. NLR and C-reactive protein were positively correlated (P < .001, P = .04, respectively) whereas serum albumin was negatively correlated (P = .009) with severe COVID-19. NLR was found to be an independent risk factor for severe COVID-19 pneumonia in the heavy group (OR = 1.264, 95% CI: 1.046~1.526, P = .015). The calculated AUC using ROC for NLR was 0.831, with an optimal limit of 4.795, sensitivity of 0.83 and specificity of 0.75, which is highly suggestive of NLR being a marker for the early detection of deteriorating severe COVID-19 infection. CONCLUSION: NLR can be used as an early warning signal for deteriorating severe COVID-19 infection and can provide an objective basis for early identification and management of severe COVID-19 pneumonia. |*COVID-19/immunology/mortality[MESH] |*Lymphocytes[MESH] |*Neutrophils[MESH] |Cross-Sectional Studies[MESH] |Humans[MESH] |Pakistan[MESH] |Pneumonia, Viral/mortality[MESH] |Prognosis[MESH] |Prospective Studies[MESH] |Retrospective Studies[MESH] |SARS-CoV-2[MESH]Neutrophil/lymphocyte ratio-A marker of COVID-19 pneumonia severity (epmc).pdf DeepDyve Pubget Overpricing