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suck abstract from ncbi


10.1111/ajt.16241

http://scihub22266oqcxt.onion/10.1111/ajt.16241
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32881315!7436464!32881315
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suck abstract from ncbi

pmid32881315      Am+J+Transplant 2020 ; 20 (11): 3072-3080
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  • COVID-19 in lung transplant recipients: A single center case series from New York City #MMPMID32881315
  • Aversa M; Benvenuto L; Anderson M; Shah L; Robbins H; Pereira M; Scheffert J; Carroll M; Hum J; Nolan M; Reilly G; Lemaitre P; Stanifer BP; D'Ovidio F; Sonett J; Arcasoy S
  • Am J Transplant 2020[Nov]; 20 (11): 3072-3080 PMID32881315show ga
  • There are limited data describing COVID-19 in lung transplant recipients. We performed a single center, retrospective case series study of lung transplant patients followed by the Columbia Lung Transplant program who tested positive for SARS-CoV-2 between March 19 and May 19, 2020. Thirty-two lung transplant patients developed mild (16%), moderate (44%), or severe (41%) COVID-19. The median age of patients was 65 years, and the median time from lung transplant was 5.6 years. Symptoms included cough (66%), dyspnea (50%), fever (47%), and gastrointestinal upset (44%). Patients received hydroxychloroquine (84%), azithromycin (75%), augmented steroids (44%), tocilizumab (19%), and remdesivir (9%). Eleven patients (34%) died at a median time of 14 days from admission. Complications during admission included: acute kidney injury (63%), transaminitis (31%), shock (31%), acute respiratory distress syndrome (25%), neurological events (25%), arrhythmias (22%), and venous thromboembolism (9%). Compared to patients with moderate COVID-19, patients with severe COVID-19 had higher peak white blood cell counts (15.8 vs 7 x 10(3) /uL, P = .019), C-reactive protein (198 vs. 107 mg/L, P = .010) and D-dimer (8.6 vs. 2.1 ug/mL, P = .004) levels, and lower nadir lymphocyte counts (0.09 vs. 0.4 x 10(3) /uL, P = .006). COVID-19 is associated with severe illness and a high mortality rate in lung transplant recipients.
  • |*Lung Transplantation[MESH]
  • |*Pandemics[MESH]
  • |*SARS-CoV-2[MESH]
  • |*Transplant Recipients[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antibodies, Monoclonal, Humanized/*therapeutic use[MESH]
  • |Antiviral Agents/therapeutic use[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Female[MESH]
  • |Graft Rejection/epidemiology/*prevention & control[MESH]
  • |Humans[MESH]
  • |Immunosuppression Therapy/methods[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |New York City/epidemiology[MESH]
  • |Retrospective Studies[MESH]


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