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10.1590/1984-0462/2020/38/2020165

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suck abstract from ncbi


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pmid32876282      Rev+Paul+Pediatr 2020 ; 38 (ä): e2020165
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  • MULTISYSTEM INFLAMMATORY SYNDROME IN A CHILD ASSOCIATED WITH CORONAVIRUS DISEASE 19 IN THE BRAZILIAN AMAZON: FATAL OUTCOME IN AN INFANT #MMPMID32876282
  • Farias ECF; Justino MCA; Mello MLFMF
  • Rev Paul Pediatr 2020[]; 38 (ä): e2020165 PMID32876282show ga
  • OBJECTIVE: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. These cases are reported as presenting the Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19. In this study, we describe with parental permission a case of MIS-C in an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. CASE DESCRIPTION: A seven-month-old infant, with SARS-CoV-2 infection and a history of extreme preterm birth and very low weight at birth, with an initial course of mild respiratory symptoms and abrupt progression to vasoplegic shock, myocarditis and hyperinflammation syndrome, shown by high levels of troponin I, ferritin, CRP, D-dimer and hypoalbuminemia. Despite the intensive care provided, the child developed multiple organ dysfunction and died. COMMENTS: Patients with a history of extreme prematurity may present with MIS-C in the presence of COVID-19 and are a group of special concern.
  • |*Coronavirus Infections/blood/diagnosis/physiopathology/therapy[MESH]
  • |*Multiple Organ Failure/etiology/therapy[MESH]
  • |*Pandemics[MESH]
  • |*Pneumonia, Viral/blood/physiopathology/therapy[MESH]
  • |*Resuscitation/methods[MESH]
  • |*Shock/etiology/therapy[MESH]
  • |*Systemic Inflammatory Response Syndrome/therapy/virology[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Deterioration[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Fatal Outcome[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Low Birth Weight[MESH]
  • |Infant, Newborn[MESH]
  • |Infant, Newborn, Diseases[MESH]
  • |Premature Birth[MESH]
  • |Respiration, Artificial/methods[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2[MESH]


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