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10.1063/5.0015626 http://scihub22266oqcxt.onion/10.1063/5.0015626 32872802!7585451!32872802     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Chaos 2020 ; 30 (8): 081104 Nephropedia Template TP {{tp|p=32872802|t=2020. Fractional diffusion on the human proteome as an alternative to the multi-organ damage of SARS-CoV-2 |pdf=|usr=}}{{32872802}} gab.com Text Fractional diffusion on the human proteome as an alternative to the multi-organ damage of SARS-CoV-2 JO: Chaos http://www.kidney.de/pget.php?&tw=1&pmid=32872802 #FOAvip The coronavirus 2019 (COVID-19) respiratory disease is caused by the novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which uses the enzyme ACE2 to enter human cells. This disease is characterized by important damage at a multi-organ level, partially due to the abundant expression of ACE2 in practically all human tissues. However, not every organ in which ACE2 is abundant is affected by SARS-CoV-2, which suggests the existence of other multi-organ routes for transmitting the perturbations produced by the virus. We consider here diffusive processes through the protein-protein interaction (PPI) network of proteins targeted by SARS-CoV-2 as an alternative route. We found a subdiffusive regime that allows the propagation of virus perturbations through the PPI network at a significant rate. By following the main subdiffusive routes across the PPI network, we identify proteins mainly expressed in the heart, cerebral cortex, thymus, testis, lymph node, kidney, among others of the organs reported to be affected by COVID-19. Twit Text FOAVip Fractional diffusion on the human proteome as an alternative to the multi-organ damage of SARS-CoV-2 ????Chaos http://www.kidney.de/pget.php?&tw=1&pmid=32872802 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32872802 #FOAvip English Wikipedia <ref>{{Cite pmid|32872802}}</ref> Fractional diffusion on the human proteome as an alternative to the multi-organ damage of SARS-CoV-2 #MMPMID32872802 Estrada E Chaos 2020[Aug]; 30 (8): 081104 PMID32872802show ga The coronavirus 2019 (COVID-19) respiratory disease is caused by the novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which uses the enzyme ACE2 to enter human cells. This disease is characterized by important damage at a multi-organ level, partially due to the abundant expression of ACE2 in practically all human tissues. However, not every organ in which ACE2 is abundant is affected by SARS-CoV-2, which suggests the existence of other multi-organ routes for transmitting the perturbations produced by the virus. We consider here diffusive processes through the protein-protein interaction (PPI) network of proteins targeted by SARS-CoV-2 as an alternative route. We found a subdiffusive regime that allows the propagation of virus perturbations through the PPI network at a significant rate. By following the main subdiffusive routes across the PPI network, we identify proteins mainly expressed in the heart, cerebral cortex, thymus, testis, lymph node, kidney, among others of the organs reported to be affected by COVID-19. |*Betacoronavirus[MESH] |*Models, Biological[MESH] |*Protein Interaction Mapping[MESH] |*Protein Interaction Maps[MESH] |*Proteome[MESH] |Biomarkers/metabolism[MESH] |COVID-19[MESH] |Coronavirus Infections/metabolism/*physiopathology[MESH] |Diffusion[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/metabolism/*physiopathology[MESH] |SARS-CoV-2[MESH]Fractional diffusion on the human proteome as an alternative to the mu(epmc).pdf DeepDyve Pubget Overpricing