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10.3390/microorganisms8091323 http://scihub22266oqcxt.onion/10.3390/microorganisms8091323 32872640!7564962!32872640     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Microorganisms 2020 ; 8 (9): ä Nephropedia Template TP {{tp|p=32872640|t=2020. Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection |pdf=|usr=}}{{32872640}} gab.com Text Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection JO: Microorganisms http://www.kidney.de/pget.php?&tw=1&pmid=32872640 #FOAvip Coronaviruses are RNA viruses that cause significant disease within many species, including cattle. Bovine coronavirus (BCoV) infects cattle and wild ruminants, both as a respiratory and enteric pathogen, and possesses a significant economic threat to the cattle industry. Transcription factors are proteins that activate or inhibit transcription through DNA binding and have become new targets for disease therapies. This study utilized in silico tools to identify potential transcription factors that can serve as biomarkers for regulation of BCoV pathogenesis in cattle, both for testing and treatment. A total of 11 genes were identified as significantly expressed during BCoV infection through literature searches and functional analyses. Eleven transcription factors were predicted to target those genes (AREB6, YY1, LMO2, C-Rel, NKX2-5, E47, RORAlpha1, HLF, E4BP4, ARNT, CREB). Function, network, and phylogenetic analyses established the significance of many transcription factors within the immune response. This study establishes new information on the transcription factors and genes related to host-pathogen interactome in BCoV infection, particularly transcription factors YY1, AREB6, LMO2, and NKX2, which appear to have strong potential as diagnostic markers, and YY1 as a potential target for drug therapies. Twit Text FOAVip Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection ????Microorganisms http://www.kidney.de/pget.php?&tw=1&pmid=32872640 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32872640 #FOAvip English Wikipedia <ref>{{Cite pmid|32872640}}</ref> Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection #MMPMID32872640 Morenikeji OB; Strutton E; Wallace M; Bernard K; Yip E; Thomas BN Microorganisms 2020[Aug]; 8 (9): ä PMID32872640show ga Coronaviruses are RNA viruses that cause significant disease within many species, including cattle. Bovine coronavirus (BCoV) infects cattle and wild ruminants, both as a respiratory and enteric pathogen, and possesses a significant economic threat to the cattle industry. Transcription factors are proteins that activate or inhibit transcription through DNA binding and have become new targets for disease therapies. This study utilized in silico tools to identify potential transcription factors that can serve as biomarkers for regulation of BCoV pathogenesis in cattle, both for testing and treatment. A total of 11 genes were identified as significantly expressed during BCoV infection through literature searches and functional analyses. Eleven transcription factors were predicted to target those genes (AREB6, YY1, LMO2, C-Rel, NKX2-5, E47, RORAlpha1, HLF, E4BP4, ARNT, CREB). Function, network, and phylogenetic analyses established the significance of many transcription factors within the immune response. This study establishes new information on the transcription factors and genes related to host-pathogen interactome in BCoV infection, particularly transcription factors YY1, AREB6, LMO2, and NKX2, which appear to have strong potential as diagnostic markers, and YY1 as a potential target for drug therapies. äDissecting Transcription Factor-Target Interaction in Bovine Coronavir(epmc).pdf DeepDyve Pubget Overpricing