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10.1097/MD.0000000000021927

http://scihub22266oqcxt.onion/10.1097/MD.0000000000021927
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32871931!7458228!32871931
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suck abstract from ncbi


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pmid32871931      Medicine+(Baltimore) 2020 ; 99 (35): e21927
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  • Efficacy and safety of traditional Chinese medicine combined with routine western medicine for the asymptomatic novel coronavirus disease (COVID-19): A Bayesian network meta-analysis protocol #MMPMID32871931
  • Wang J; Zhu X; Sun Y; Zhang X; Zhang W
  • Medicine (Baltimore) 2020[Aug]; 99 (35): e21927 PMID32871931show ga
  • BACKGROUND: The number of patients infected with novel coronavirus disease (COVID-19) has exceeded 10 million in 2020, and a large proportion of them are asymptomatic. At present, there is still no effective treatment for this disease. Traditional Chinese medicine (TCM) shows a good therapeutic effect on COVID-19, especially for asymptomatic patients. According to the search results, we found that although there are many studies on COVID-19, there are no studies targeting asymptomatic infections. Therefore, we design a network meta-analysis (NMA) to evaluate the therapeutic effect of TCM on asymptomatic COVID-19. METHODS: We will search Chinese and English databases to collect all randomized controlled trials (RCTs) of TCM combined with conventional western medicine or using only TCM to treat asymptomatic COVID-19 from December 2019 to July 2020. Then, two investigators will independently filter the articles, extract data, and evaluate the risk of bias. We will conduct a Bayesian NMA to evaluate the effects of different therapies. All data will be processed by Stata 16.0 and WinBUGS. RESULTS: This study will evaluate the effectiveness of various treatments for asymptomatic COVID-19. The outcome indicators include the time when the nucleic acid turned negative, the proportion of patients with disease progression, changes in laboratory indicators, and the side effects of drugs. CONCLUSION: This analysis will further improve the treatment of asymptomatic COVID-19. INPLASY REGISTRATION NUMBER: INPLASY202070022.
  • |Asymptomatic Infections/therapy[MESH]
  • |Bayes Theorem[MESH]
  • |Betacoronavirus/drug effects/isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |Combined Modality Therapy/*methods[MESH]
  • |Coronavirus Infections/drug therapy/*therapy[MESH]
  • |Humans[MESH]
  • |Medicine, Chinese Traditional/*methods[MESH]
  • |Network Meta-Analysis[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*therapy[MESH]
  • |Research Design[MESH]
  • |SARS-CoV-2[MESH]


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