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10.1016/j.heliyon.2020.e04793 http://scihub22266oqcxt.onion/10.1016/j.heliyon.2020.e04793 32869005!7448739!32869005     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Heliyon 2020 ; 6 (8): e04793 Nephropedia Template TP {{tp|p=32869005|t=2020. A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2 |pdf=|usr=}}{{32869005}} gab.com Text A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2 JO: Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=32869005 #FOAvip The -1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces the survival of the virus. This study aimed to successfully develop a toolkit for screening antiviral drugs. Finally, the FDA-approved drug library was screened, revealing that ivacaftor and (-)-Huperzine A worked well in changing the -1 ribosomal frameshifting of SARS-CoV-2 in vitro. Twit Text FOAVip A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2 ????Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=32869005 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32869005 #FOAvip English Wikipedia <ref>{{Cite pmid|32869005}}</ref> A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2 #MMPMID32869005 Chen Y; Tao H; Shen S; Miao Z; Li L; Jia Y; Zhang H; Bai X; Fu X Heliyon 2020[Aug]; 6 (8): e04793 PMID32869005show ga The -1 ribosomal frameshifting is vital for the translation of the open reading frame (ORF)1b in SARS-CoV-2. The products of ORF1b participate in viral replication. Therefore, changing the frameshift frequency reduces the survival of the virus. This study aimed to successfully develop a toolkit for screening antiviral drugs. Finally, the FDA-approved drug library was screened, revealing that ivacaftor and (-)-Huperzine A worked well in changing the -1 ribosomal frameshifting of SARS-CoV-2 in vitro. äA drug screening toolkit based on the -1 ribosomal frameshifting of SA(epmc).pdf DeepDyve Pubget Overpricing